Journal of Food and Nutrition Research
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Journal of Food and Nutrition Research. 2019, 7(1), 41-50
DOI: 10.12691/jfnr-7-1-6
Open AccessReview Article

The Role of Diet in Maintaining Strong Brain Health by Taking the Advantage of the Gut-brain Axis

Sahithi Madireddy1 and Samskruthi Madireddy1,

1353 Tanaka Drive, San Jose, CA 95131, USA

Pub. Date: January 24, 2019

Cite this paper:
Sahithi Madireddy and Samskruthi Madireddy. The Role of Diet in Maintaining Strong Brain Health by Taking the Advantage of the Gut-brain Axis. Journal of Food and Nutrition Research. 2019; 7(1):41-50. doi: 10.12691/jfnr-7-1-6


A healthy and diverse gut microbiota is essential for host health. Recent studies indicate that the gut microbiota play a significant role in signaling the gut-brain axis, and thereby having a significant impact on the brain, which is a part of the central nervous system (CNS). As the concept of the gut-brain-axis is now relatively well-established, attention has turned to the effects of diets on the gut-brain-axis. While functions of the gut-brain-axis have been studied, the potential impact of diet on brain health, as part of the gut-brain-axis, remains underexplored. Indeed, a limited body of evidence supports a role for diet, prebiotics, and probiotics in influencing the gut-brain-axis. This review focuses on nutrients and bio-active substances such as iron, fiber, short chain fatty acids, vitamins, polyphenols, zinc, and probiotics and their protective effects on brain health. Understanding the influence of diet on the gut-brain-axis will shed light on the conditions wherein brain health can be maintained by altering diet.

microbiota gut-brain axis nutrition diet brain fatty acids

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