Abstract: Synchronous primary colorectal cancer is rare and only occurs in 2% to 11% of all colorectal cancers. Thus, preoperative or intraoperative detection of synchronous tumor is vital because if they are not recognized, they may present at an advanced stage, thereby reduce the probability of cure. Early identification of synchronous tumor may alter the extensiveness of the surgical procedure in order to decide for strategic therapeutic management.

Abstract: Mantle cell lymphoma is a relatively rare disease, mostly affecting the elderly. It behaves aggressively although it has features of an indolent lymphoma. Here, we presented a case of an 85-year old female patient applying to emergency service with difficulty in breathing due to huge lumps around her neck. She had mantle cell lymphoma which has aggressively progressed despite chemotherapy. She was at an advanced stage of the disease and taken to the intensive care unit. Despite best supportive care, steroid therapy and respiratory support, she passed away within 24 hours.

Abstract: For the last many decades pernicious anemia has been treated as a separate clinical feature. Pernicious anemia is also known as macrocytic anemia which originates due to the lack of vitamin B12 (cobalamin). A protein called intrinsic factor which helps vitamin B12 for its absorption through terminal ileum so, the deficiency of intrinsic factor result in a lack of vitamin B12 absorption, which, in turn, causes pernicious anemia. The gastric parietal cell normally produces chlorhydric acid and intrinsic factor. Atrophic body gastritis (ABG) is a condition which cause the destruction of the oxyntic mucosa and the reduction of the parietal cell hence result in the deficiency of intrinsic factor . Pernicious anemia can present in many different clinical patterns like fatigue (tiredness), headache, dizziness, shortness of breath, pale or yellowish skin, coldness in your hands and feet, and chest pain. Presentation of Case: We report a case of a 55 year old male who presented with one month history of fatigue ness, dizziness, abdominal pain and short of breath on exertion. On further investigation, it is turnout to be atrophic gastritis which is treated conservatively.

Abstract: A rare case of non-Hodgkin's lymphoma (NHL) complicated with marked hypercalcemia caused by parathyroid hormone related protein (PTHrP) and presenting with Adams-Stokes attack is reported. A 72-year-old woman was involved in a traffic accident, and was transferred to our hospital. Blood examination revealed marked hypercalcemia (5.3 mmol/l (21.3 mg/dl)). A diagnosis of NHL (B-cell lymphoma, clinical stage IVA) was made by the results of the bone marrow biopsy, CT features showing multiple masses, and the gallium scintigraphy showing strong accumulation. Because of high blood level of PTHrP, hypercalcemia was considered to be due to PTHrP as a mediator acting on calcium metabolism. Hypercalcemia complicated with malignancy has a risk resulting in a fatal outcome. In the cases of malignant lymphoma complicated with hypercalcemia, we should pay attention to PTHrP as a mediator.

Abstract: We describe results of intravitreal moxifloxacin in a case of acute post traumatic endophthalmitis & cataract developed after sustaining a penetrating ocular injury. Management included topical and intravitreal moxifloxacin. The intravitreal injection was given at the time of presentation and then was repeated after 48 hours when lens aspiration and anterior vitrectomy was performed. The patient showed a rapid recovery, and achieved 6/6 vision following surgery. To our knowledge this is the first reported case of therapeutic use of intravitreal moxifloxacin in a human case of acute post traumatic endophthalmitis. Presentation of Case: We report a case of a twenty one year old male referred to us with two days history of penetrating injury in left eye due to a piece of metallic wire. After five days of hospitalization, he was discharged with 6/6 partial best corrected vision. Consent: The patient and his family have given informed consent for the publication of this case report.