Journal of Food and Nutrition Research
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Journal of Food and Nutrition Research. 2017, 5(6), 413-417
DOI: 10.12691/jfnr-5-6-8
Open AccessArticle

Ethanol Extract of Eriobotrya japonica Leaves Enhanced Swimming Capacity in Mice

Heesun Jeong1, Ok-Kyung Kim1, Jeongjin Park1, Kyungmi Kim2, Jin Woong Chung3, Sangin Shim4, Yanghee You1, and Woojin Jun1,

1Division of Food and Nutrition, Chonnam National University, Gwangju, Republic of Korea

2Department of Biofood Analysis, Korea Bio Polytechnic, Ganggyung, Republic of Korea

3Department of Biological Science, Dong-A University, Busan, Republic of Korea

4Division of Agriculture and Life Sciences, Gyeongsang National University, Jinju, Republic of Korea

Pub. Date: May 31, 2017

Cite this paper:
Heesun Jeong, Ok-Kyung Kim, Jeongjin Park, Kyungmi Kim, Jin Woong Chung, Sangin Shim, Yanghee You and Woojin Jun. Ethanol Extract of Eriobotrya japonica Leaves Enhanced Swimming Capacity in Mice. Journal of Food and Nutrition Research. 2017; 5(6):413-417. doi: 10.12691/jfnr-5-6-8


Eriobotrya japonica is known as ‘Loquat’ and cultivated in Korea, China, Japan, and India. The present study aims to investigate the effect of Eriobotrya japonica leaves ethanol extract (EJLE) on swimming capacity in mice. Mice were administered distilled water (EX-CON) or 1 g kg-1 per day of EJLE (EX-EJLE) for 14 days. Exhaustive swimming time was significantly prolonged (by 1.4-fold) in EX-EJLE group compared to that in EX-CON group (P < 0.05). EX-EJLE group showed high nonesterified fatty acid (NEFA) and glycogen levels during swimming (P < 0.05). When compared to EX-CON, the EX-EJLE exhibited significant increases in antioxidant enzymes activities including catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) and glutathione (GSH) level as well as and decrease in malondialdehyde (MDA) level (P < 0.05). EJLE elevated the mRNA expression of carnitine palmitoyltransferase-1, β-hydroxyacyl coenzymes dehydrogenase, peroxisomal proliferator activated receptors-δ, and uncoupling protein-3 in muscle (P < 0.05). These results suggest that EJLE supplementation could improve swimming capacity by ameliorate the physical exhaustion through enhancing utilization of fatty acid, facilitating lipid catabolism, and elevating antioxidant capability.

eriobotrya japonica leaves ethanol extract swimming capacity

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