Comparison of Antifatigue Activity of Five Sea Cucumber Species in a Mouse Model of Intense Exercise

Jitima Suwanmala^{1, 2}, Shangyun Lu¹, Qingjuan Tang¹, Charuay Sukhsangchan², Rong Zheng¹, Suriyan Tunkijjanukij^3, and Changhu Xue^1,

¹College of Food Science and Engineering, Ocean University of China, Qingdao, P.R. China

²Department of Marine Science, Faculty of Fisheries, Kasetsart University, Bangkok, Thailand

³Department of Aquaculture, Faculty of Fisheries, Kasetsart University, Bangkok, Thailand

Cite this paper:
Jitima Suwanmala, Shangyun Lu, Qingjuan Tang, Charuay Sukhsangchan, Rong Zheng, Suriyan Tunkijjanukij and Changhu Xue. Comparison of Antifatigue Activity of Five Sea Cucumber Species in a Mouse Model of Intense Exercise. Journal of Food and Nutrition Research. 2016; 4(1):12-19. doi: 10.12691/jfnr-4-1-3

Abstract

Background: Sea cucumber (class Holothuroidea, phylum Echinodermata) is a marine food rich in valuable nutrients and is confirmed to have antifatigue effects. This study aimed to compare the antifatigue activity of five sea cucumber species from China and Thailand. Materials and Methods: A mouse model of effective intense exercise was used. Blood levels of lactic acid (LA), and creatine kinase (CK), liver and muscle glycogen content, malondialdehyde (MDA) content and blood superoxide dismutase (SOD) activity were investigated. Results: Holothuria scabra (Thailand) supplementation decreased blood LA and CK levels from 9.17 ± 0.59 and 0.52 ± 0.03 to 7.82 ± 0.97 mmol/L and 0.40 ± 0.08 U/ml, respectively and increased liver and muscle glycogen levels after intense exercise from 10.70 ± 0.18 and 0.93 ± 0.02 to 14.57 ± 1.61 and 1.02 ± 0.06 mg/g, respectively. Identical results were also obtained in the popular Chinese species A. japonicas. Furthermore, A. japonicus and Thenenota ananas supplementation decreased MDA content significantly (p<0.01 and p<0.05, respectively). A. japonicus, H. scabra, Acaudina molpadioides and Cucumaria frondosa supplementation significantly increased SOD level. Conclusion: The five sea cucumber species, especially A. japonicus and H. scabra, display good antifatigue activities.

Keywords:
Holothuroidea antifatigue antioxidant exercise performance mouse model

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