Abstract: School-age children and adolescents were examined (2010-2011). Totally we include in investigation 15067 Moscow schoolchildren from all Moscow regions, 7760 were boys and 7307 were girls. Height, weight and other anthropometric data were obtained from participants (6-17 years old). It was found that number of girls with overweight was higher 20% of population. Number of girls with obesity is growing up from age 6 to 9 years old. Number of boys with overweight was some lower than number of girls; it also was near 20% of populations. Number of boys with obesity is growing up from 6 till 11 years old. The greatest difference between groups with and without obesity was shown by the abdominal and subscapular skinfolds. It shows that cardiovascular risk factors appear along with obesity in childhood and adolescence.

Abstract: Ultraviolet B (UVB) radiation is a potent environmental factor in skin pathogenesis as it modulates oxidative burst, gene expression and proliferation/apoptosis of human normal keratinocytes. In the absence of cell apoptosis, sublethal UVB is shown to induce significant increase of mitochondrial and nuclear DNA lesions as quantified by increased apurinic/apyrimidinic sites together with transcriptomic modulation of pro-apoptosis/survival genes. These effects may be attenuated by cell pretreatment with extracts from three various plants: Papaver rhoeas, Passiflora incarnata and Anchusa arvensis or their mixture. Extracts variably decreased UVB-induced mitochondrial and nuclear DNA lesions in normal human keratincoytes. When mixed together, higher reduction of DNA lesions has been observed at lower extracts’ concentrations, compared to each extract alone which suggested their synergy. Furthermore, sublethal UVB-induced transcriptomic modulation was significantly prevented by cell preincubation with extract mixture through coordinated reduction of pro-apoptotic gene transcription while increasing pro-survival related transcripts. Finally, extract mixture protected keratinocytes against lethal UVB dose. This work reveals sublethal UVB-mediated lesions at both DNA and RNA levels in human keratinocytes and the ability of appropriate plant-derived sunscreen to reduce cell injury.

Abstract: Private health sector has the potential to ease the increasing burden on public health resources brought about by scaling-up of HIV treatment and care services. However, quality concerns have limited its role. A cross-sectional study comparing patients’ satisfaction with quality of anti-retroviral services between public and private health-care facilities was carried out. Using an adapted Patient Satisfaction Questionnaire III, exit interviews were conducted for 809 consecutive adult HIV positive patients. Patients spent significantly less time visiting public health facility compared to private health facility. Median time spent waiting to see a doctor in public health facility was half of the time spent in private health facility. Patients on anti-retroviral drugs in public health facility spent significantly less time to collect drugs compared to patients in private health facility. Mean satisfaction scores of patients who attended public health facility were higher than scores of patients who attended private health facility in general satisfaction, technical quality of services provided, interpersonal manner, communication and time spent with doctor domains. Dissatisfaction with antiretroviral services in private health facilities could threaten attainment of anti-retroviral treatment objectives. Private health sector integration into HIV treatment services might improve service delivery and promote good clinical practice.

Abstract: The range of research has augmented significantly through the last five to six decades and ethics has turned out to be central issue in different disciplines. Ethics supported on elementary human values for the involvement of human participants in the research. However, rising difficulty of different research and ethical codes are incompatible at certain points; the basic principles and codes need to be adjusted. This article illustrates some of the ethical dilemmas and challenges that have been addressed primarily in the research including human participants in different settings. This article chiefly highlighted the lively of gaining interviewees’ faith in a community, snags of ethical principles and concludes with some ethical dilemmas and challenges experienced by the researcher. Prediction of ethical challenges and dilemmas are not always possible. Therefore, the researcher must be persistently alert of the continuing impact that the research might have on those involved, while concurrently being ethically responsive and morally capable.

Abstract: There are vast inequalities across maternal and infant mortality with the developing world accounting for the majority of the burden. Within countries there are also disparities between urban and rural populations with rural populations expecting worse maternal outcomes. These inequalities are linked to health care service delivery, with this review focusing on obstetric ultrasound and its potential to improve maternal and newborn health in low resource settings. Access to obstetric ultrasound in the developed world is almost universal, identifying potential obstetric risks to contribute to improvements in maternal and newborn health outcomes. In contrast to this access to obstetric ultrasound in the developed world is poor, particularly in rural areas. Considerations for service provision in these areas are vastly different to the developed world and include infrastructure, economic resources, training and cultural acceptability. Innovations in teleradiology and portable ultrasound offer opportunity for improved ultrasound access in low resource settings potentially improving maternal care and outcomes. The versatility of ultrasound also offers a wide range of non-obstetric clinical applications. This review demonstrates promising benefits of obstetric ultrasound in poorly resourced settings. The literature also shows a need for large scale trials in limited resource settings, particularly in rural and remote areas.

Abstract: Vietnam, like many other developing countries experiences over whelming challenges related to Human Immunodeficiency Virus (HIV) infections, including significant stigma and discrimination of people who are affected by HIV infections. HIV pandemic has resulted in increased numbers of Orphans and Vulnerable Children (OVC). Different strategies are required in addressing these challenges. The aim of this paper is to review the literature and describe interventions aimed to decrease HIV stigma and discrimination in OVC. The focus is to identify aspects of these interventions that are effective in Vietnam. The findings demonstrate that the Vietnam government and international agencies such as the UNAIDS and UNICEF are employing joint strategies to address the growing problems of OVC in the country. This has included increased care and treatment programs, provision of Information-Education-Communication programs, encouraging parents and peers in reducing HIV stigma and discrimination, utilizing Non- Governmental Organisations’ support, and improving policy intervention on HIV stigma and discrimination reduction.

Abstract: Immigrant communities are often not well served when it comes to mental health services. A fundamental reason for this may lie in differing cultural concepts of what it means to be healthy. The aim of this paper is to capture how Sri Lankan Tamils with a diagnosis of depression, newly arrived to Toronto, Canada, conceptualize health, and to determine whether this conceptualization is shared by care providers who provide service to this community. The data are derived from a qualitative study based on interviews with 16 Sri Lankan Tamil immigrants who self-report being diagnosed with depression and 8 service providers who work with the community. Findings show that the Sri Lankan Tamil community emphasizes social functioning as the hallmark of health. Study participants see depression as linked to a breakdown in social functioning. The community also holds an integrated notion of health, one that encompasses physical, mental and social components. Responses show little evidence for a belief in the role of the supernatural in causing mental illness. Medication is seen as part and parcel of ill health; it is sought during overt illness but its preventive action is not well understood. Service providers do not fully understand the community’s notions of health and illness. It can be surmised that the social dimensions of health and illness are fundamental to this community. Being well means being able to fulfil one’s social role. This suggests that the provision of social support services, vocational services for instance, needs to be a key component of mental health services. Acculturation into concepts of preventive health including the role of medication in maintaining health and preventing relapse is also important.

Abstract: Background: Periodontitis has been identified as potential risk factors for systemic pathologies. The aim of this study was to investigate the relationship between periodontitis and systemic inflammatory markers, as well as, if there is a relation to severity of periodontitis. Methodology: Periodontal examinations and serum markers of inflammation levels mesaurements were performed in 50 patients. The patients with moderate periodontitis had low CAL and PD < 5mm. The patients with severe periodontitis were with high CAL and PD > 5mm. The clinical parameters of periodontitis were determined among all subjects. The LEU, CRP, and FIB for the present investigation were obtained from peripheral venous blood patients from all groups. Findings: In both moderate and severe periodontitis, the results indicated that the total leukocytes count and neutrophils had a significantly higher count (p < 0.001) among the groups with periodontitis but that there was no significance in the lymphocytes counts. The results also show a significant relation between indicators of poor periodontal status and increased levels CRP and fibrinogen. Conclusion: Periodontitis is associated with an enhanced inflammatory response expressed by higher levels of inflammatory markers. The extent of increase in these marker levels in periodontitis patients depends of severity of the disease. Significance: The association of periodontitis with WBC, CRP and fibrinogen levels appears to be contributing factors for CVD and might be a possible intermediate pathway in this association.

Abstract: In the Sochi sanatoriums, 609 patients with coronary heart disease, hypertensive disease, diabetes, metabolic syndrome and various combinations of these diseases were examined. The traditional and optimized medical complexes were used. The optimization implied the joining balneotherapy and climate therapy, therapeutic physical training and diet therapy, bioresonance therapy, “Magnerot” medicinal product, hypoxytherapy, hypercapnotherapy, “Arfazetin” herbal tea and “Chvizhepse” mineral water. The studies have shown that the use of optimized treatment program is more efficient, than the traditional one for patients of all groups.