Banana Intake Relieves the Stress of Daily Life in Healthy Adult Volunteers: An Open, Randomized, Parallel-Group Comparative Study

Akiko Kobayashi¹, Ailing Hu^2, , Takuji Yamaguchi², Masahiro Tabuchi², Yasushi Ikarashi² and Hiroyuki Kobayashi²

¹Medical Corporation Association Junkokai, Kobayashi Medical Clinic Tokyo, Tokyo 107-0052, Japan

²Personalized Kampo Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan

Cite this paper:
Akiko Kobayashi, Ailing Hu, Takuji Yamaguchi, Masahiro Tabuchi, Yasushi Ikarashi and Hiroyuki Kobayashi. Banana Intake Relieves the Stress of Daily Life in Healthy Adult Volunteers: An Open, Randomized, Parallel-Group Comparative Study. Journal of Food and Nutrition Research. 2022; 10(12):841-849. doi: 10.12691/jfnr-10-12-2

Abstract

Bananas are a well-balanced typical prebiotic food rich in dietary fiber, oligosaccharides, vitamins, and minerals. However, evidence supporting the stress-relieving effects of banana consumption in daily life is scarce. Therefore, we investigated the effects of banana-intake on stress-related markers, such as the intestinal environment, biochemical markers, autonomic balance, and mood status, in an open, randomized, parallel-group controlled trial using 20 healthy adult volunteers divided into a banana-intake group (n = 13 subjects, two bananas daily for 2 weeks) and a non-intake control group (n = 7, no banana-intake for 2 weeks). We measured the intestinal environmental marker urinary indoxyl sulfate, stress markers (salivary cortisol and chromogranin A), autonomic nervous system activity markers (heart rate, natural logarithm of low-frequency power [LnLF], natural logarithm of high-frequency power [LnHF], and LnLF/LnHF ratio), and mood status before and after the 2-week experimental period. We assessed the rate of change before and after banana-intake for all parameters by performing comparisons between the banana-intake and the non-intake control group as well as between the effective and ineffective groups within the banana-intake group. There was no significant difference in the rate of change for all parameters before and after banana-intake compared with the non-intake group. However, approximately 50% of the banana-intake group showed decreased urinary indoxyl sulfate; decreased cortisol and chromogranin A levels; decreased heartbeat and LnLF power, increased LnHF power, and decreased LnLF/LnHF ratio; a decrease in the five negative subscales, an increase in the two positive subscales, and a decrease in total mood disorder score. Our findings suggest that banana-intake for 2 weeks improves the intestinal environment, leads to predominant parasympathetic activity, and provides stress relief and psychological stability in approximately 50% of healthy adults.

Keywords:
banana prebiotics intestinal environment stress autonomic nervous mood

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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