The Effect of Diets Enriched with Avocado (Persea americana cv Hass) on Cholesterol and Triglyceride Decrease Evaluated in Hamsters

José Octavio Rodiles-López¹, Marcela González-Montoya^1, , Héctor Eduardo Martínez-Flores¹ and Rafael Zamora-Vega¹

¹Facultad de Químico Farmacobiología. Tzintzuntzan 173. Col. Matamoros. C.P. 58240. Universidad Michoacana de San Nicolás de Hidalgo. Morelia, México

Cite this paper:
José Octavio Rodiles-López, Marcela González-Montoya, Héctor Eduardo Martínez-Flores and Rafael Zamora-Vega. The Effect of Diets Enriched with Avocado (Persea americana cv Hass) on Cholesterol and Triglyceride Decrease Evaluated in Hamsters. Journal of Food and Nutrition Research. 2020; 8(11):670-674. doi: 10.12691/jfnr-8-11-7

Abstract

Avocados are characterized by their high dietary fiber and unsaturated fatty acids content. This study aimed to evaluate the hypolipidemic and hypocholesterolemic effect of avocado Hass on hamsters fed with diets based on freeze-dried pulp avocado (FAD) and defatted paste avocado (DPAD). Total cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), serum triglycerides (TG), and atherogenic index of plasma (AIP) were evaluated along with total lipids in liver and feces. Compared to the control diet, FAD and DPAD reduced the serum TG levels by 76.47 and 46.06%, respectively. FAD also reduced the serum TC levels by 16.39%. FAD and DPAD decreased the lipids in the liver by 33.61% and 10.0% and the amount of lipid excreted in feces by 73.47% and 41.50%, respectively. FAD showed the lowest AIP, 0.60, compared to that of DPAD and the control, 1.83 and 1.94, respectively. Freeze-dried avocado pulp was found to be efficient in reducing dyslipidemia values in hamsters.

Keywords:
avocado freeze-drying hamsters triglycerides cholesterol

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