International Journal of Hematological Disorders
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International Journal of Hematological Disorders. 2014, 1(1), 31-34
DOI: 10.12691/ijhd-1-1-6
Open AccessArticle

Effect of G6pd Status in Malaria Infected Individuals on Cortisol, Malondialdehyde, Blood Glucose and Blood Lipid Profile

Esan A.J1, and Ifeanyichukwu M.O2

1Haematology Department, Federal Medical Centre, Ido-Ekiti, Ekiti State Nigeria

2Immunology Department, Nnamidi Azikiwe University, Nnewi Campus

Pub. Date: November 10, 2014

Cite this paper:
Esan A.J and Ifeanyichukwu M.O. Effect of G6pd Status in Malaria Infected Individuals on Cortisol, Malondialdehyde, Blood Glucose and Blood Lipid Profile. International Journal of Hematological Disorders. 2014; 1(1):31-34. doi: 10.12691/ijhd-1-1-6


The aim of this study was to determine the effect of Glucose-6-Phosphate dehydrogenase (G6PD) status in Plasmodium falciparum malaria infected individuals cortisol, malondialdehyde (MDA), blood glucose and blood lipid profile. The study was conducted at Federal Medical Centre, Ido-Ekiti, Nigeria. Two hundred and two blood samples were collected twice from each malaria infected individuals. Thick blood film was made and stained with Giemsa’s staining technique for malaria parasite detection; Glucose-6-Phosphate dehydrogenase (G-6-PD) was performed using methaemoglobin reduction method. Data obtained was analysed using SPSS version 16. The result of this present study showed that the mean±SD of cortisol and malondialdehyde (MDA) in G6PD normal were higher compared to G6PD deficient in pre and post anti-malaria drug treatment. Cortisol levels increased in patients with P.falciparum malaria infection, which decline as the clinical condition improved and parasitaemia decrease during anti malaria treatment.

malaria parasite G6PD and anti-malaria therapy

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