International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: https://www.sciepub.com/journal/ijcd Editor-in-chief: Samasca Gabriel
Open Access
Journal Browser
Go
International Journal of Celiac Disease. 2015, 3(3), 112-114
DOI: 10.12691/ijcd-3-3-6
Open AccessArticle

Increased Knowledge and Awareness of Celiac Disease will Benefit the Elderly

Aaron Lerner1, 2, and Torsten Matthias1

1AESKU.KIPP Institute, Mikroforum Ring 2, Wendelsheim 55234, Germany.

2B. Rappaport School of Medicine, Technion-Israel Institute of Technology, Michal St, No 7, Haifa, 34362, Israel

Pub. Date: August 06, 2015

Cite this paper:
Aaron Lerner and Torsten Matthias. Increased Knowledge and Awareness of Celiac Disease will Benefit the Elderly. International Journal of Celiac Disease. 2015; 3(3):112-114. doi: 10.12691/ijcd-3-3-6

Abstract

Celiac disease, once deemed to be primarily a pediatric disease, is accepted nowadays as a lifelong disease that increasingly affects the elderly. In older patients it is late and underdiagnosed, it is hypo- or asymptomatic and case finding strategy is recommended. Gluten restrictive therapy is problematic but manageable and beneficial, improving symptoms, serology, histology and preventing complications. Increased knowledge and awareness on CD in the third age and a comprehensive, multidisciplinary and holistic approach will improve their outcome.

Keywords:
celiac disease elderly clinical presentation diagnosis therapy complication awareness

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Deleanu D, Muntean A, Baican A, Danciu P, Magurici C, Samasca G. Major problems to the clinical reassessment of celiac disease in elderly. International Journal of Celiac Disease. 2015; 3: 110-111.
 
[2]  Tai V, Crowe M, O'Keefe S. Celiac disease in older people. J Am Geriatric Soc. 2000; 48:1690-6.
 
[3]  Gabardine G, Ciccocioppo R, De Vitis I, Corazza GR; Club del Tenue Study Group. Coeliac Disease in the Elderly. A multicentre Italian study. Gerontology. 2001;47:306-10.
 
[4]  Freeman HJ. Adult celiac disease in the elderly. World J Gastroenterol. 2008;14:6911-4.
 
[5]  Lurie Y, Landau DA, Pfeffer J, Oren R. Celiac disease diagnosed in the elderly. J Clin Gastroenterol. 2008;42:59-61.
 
[6]  Rashtak S, Murray JA. Celiac disease in the elderly. Gastroenterol Clin North Am. 2009;38:433-46.
 
[7]  Singh P, Shergill S, Makharia GK. Celiac disease in older adults. J Gastrointestin Liver Dis. 2013;22:359-60.
 
[8]  Casella S, Zanini B, Lanzarotto F, Villanacci V, Ricci C, Lanzini A. Celiac disease in elderly adults: clinical, serological, and histological characteristics and the effect of a gluten-free diet. J Am Geriatr Soc. 2012;60:1064-9.
 
[9]  Mukherjee R, Egbuna I, Brar P, Hernandez L, McMahon DJ, Shane EJ, et al. Celiac disease: similar presentations in the elderly and young adults. Dig Dis Sci. 2010;55:3147-53.
 
[10]  Almeida LM, Castro LC, Uenishi RH, de Almeida FC, Fritsch PM, Gandolfi L, et al. Decreased prevalence of celiac disease among Brazilian elderly. World J Gastroenterol. 2013;19:1930-5.
 
[11]  Vilppula A, Collin P, Mäki M, Valve R, Luostarinen M, Krekelä I, et al. Undetected coeliac disease in the elderly: a biopsy-proven population-based study. Dig Liver Dis. 2008;40:809-13.
 
[12]  Vilppula A, Kaukinen K, Luostarinen L, Krekelä I, Patrikainen H, Valve R, et al. Increasing prevalence and high incidence of celiac disease in elderly people: a population-based study. BMC Gastroenterol. 2009;9:49.
 
[13]  Salmi TT, Collin P, Korponay-Szabó IR, Laurila K, Partanen J, Huhtala H, et al. Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody deposits. Gut. 2006;55:1746-53.
 
[14]  Dahle C, Hagman A, Ignatova S, Ström M. Antibodies against deamidated gliadin peptides identify adult coeliac disease patients negative for antibodies against endomysium and tissue transglutaminase. Aliment Pharmacol Ther. 2010;32:254-60.
 
[15]  Quinn CJ, Cotter PE, Stevens FM, O’Keeffe ST. Coeliac disease in the older patient. Rev in Clin Gerontol 2006;16:291-300.
 
[16]  Godfrey JD, Brantner TL, Brinjikji W, Christensen KN, Brogan DL, Van Dyke CT et al. Morbidity and mortality among older individuals with undiagnosed celiac disease. Gastroenterology. 2010;139:763-9.
 
[17]  Hankey GL, Holmes GKT. Coeliac disease in the elderly. Gut 1994;35:65-67.
 
[18]  Robson K, Alizart M, Martin J, Nagel R. Coeliac patients are undiagnosed at routine upper endoscopy. PLoS One. 2014;9:e90552.
 
[19]  Vilppula A, Kaukinen K, Luostarinen L, Krekelä I, Patrikainen H, Valve R, et al. Clinical benefit of gluten-free diet in screen-detected older celiac disease patients. BMC Gastroenterol. 2011;11:136.
 
[20]  Freeman HJ. Small bowel mucosal biopsies for case-finding in celiac disease. International Journal of Celiac Disease 2015;3:50-52.
 
[21]  Lerner A, Neidhöfer S, Matthias T. Serological markers and/or intestinal biopsies in the case-finding of celiac disease. International Journao of Celiac Disease. 2015;3:53-55.
 
[22]  Katz KD, Rashtak S, Lahr BD, Melton LJ 3rd, Krause PK, et al. Screening for celiac disease in a North American population: sequential serology and gastrointestinal symptoms. Am J Gastroenterol. 2011;106:1333-9.
 
[23]  Ludvigsson JF, Card TR, Kaukinen K, Bai J, Zingone F, Sanders DS, et al. Screening for celiac disease in the general population and in high-risk groups. United European Gastroenterol J. 2015;3:106-20.
 
[24]  Oxentenko AS, Murray JA. Celiac Disease: Ten Things That Every Gastroenterologist Should Know. Clin Gastroenterol Hepatol. 2015;13:1396-404.