An Overview on Various Aspects of Plant Berberis Lycium Royale

Suhail Ahmad Parra^1, , Kalpesh Gaur¹, Lalit Singh Ranawat¹ and Mohammad Imran Rather¹

¹Geetanjali Institute of Pharmacy, Geetanjali University, Udaipur-313002 (Rajasthan), India

Cite this paper:
Suhail Ahmad Parra, Kalpesh Gaur, Lalit Singh Ranawat and Mohammad Imran Rather. An Overview on Various Aspects of Plant Berberis Lycium Royale. American Journal of Pharmacological Sciences. 2018; 6(1):19-24. doi: 10.12691/ajps-6-1-4

Abstract

Herbal medicine is getting popularized in developing and developed countries owing to its natural origin. Berberis Lycium also famous as Indian Barberry, Kashmal in Hindi and Ishkeen in Urdu belongs to the family Berberidaceae. Its local name is Kawdach in Kashmir valley. Traditionally, Berberis lycium is used by the Tribal peoples in J&K, India, since the time immemorial. It is an evergreen spiny shrub 2-3 m in height growing mainly in Himalayan regions. The various parts of the plant like root, bark, stem, leaves and fruits are used by the people as a medicine or food. In traditional system of medicine, the plant is used for various affliction and diseases. This plant has also gained wide acceptance for its medicinal value in ayurvedic drugs. The plant is known to prevent liver disorders, abdominal disorders, skin diseases, cough, ophthalmic, oral ulcers, kidney, conjunctivitis, piles, leprosy etc. The pharmacological studies have shown that plant has hypoglycemic, antihyperlipidemic, hepatoprotective, antipyretic, wound healing, anticancer, antimicrobial, antifungal, pesticidal properties.In the present article we have summarized various aspects of the plant Berberis lycium.

Keywords:
Berberis Lycium Berberidaceae Berberine Traditional medicine Phytochemical Pharmacological activity

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]	Owolabi J EKI., Omogbai O., (2007). Antifungal and antibacterial activities of the ethanolic and aqueous extract of Kigelia Africana (Bignoniaceae) stem bark. Afr. J Biotechnology. 6(14):882-85.
[2]	Mahesh B., and Satish S., (2008). Antimicrobial Activity of Some Important Medicinal Plant against Plant IJSER and Human Pathogens, World J. Agric. Sci., 4: 839-843.
[3]	Jussieu A.L.de.(1789).Berberidaceae, nom. cons. Genera Plantarum: 286.
[4]	Bruckner C., (2000). Clarification of the Carpel Number in Papaverales, Capparales, and Berberidaceae. Botanical Review, 66(2): 155-307.
[5]	Anonymous., (1988). The wealth of India, a dictionary of Indian Raw Materials, vol. 2 (B). Publications and Information Directorate CSIR, New Delhi: 114-118.
[6]	Dhar Uppeandra., Kachroo P,. (1983). Alpine flora of Kashmir Himalaya: 180.
[7]	Irshad AH., et al. (2013). “Antibacterial activity of Berberis lycium root extract”. Trakia Journal of Sciences 11.1: 88-90.
[8]	Nyla J., Ammara S., Sadaf A., and Zaheer Hussain., (2015). Berberis lycium Royle (Royle, 1837): A Threatened Medicinal Plant and Its Biological Activities,EC Agriculture 1.2; 100-108.
[9]	Purvika, S., Rajni, M., and Monika, S., (2013). Berberis lycium a plant with immense value, Indian Journal of pharmaceutical and Biological reasearch (IJPBR), Vol I.: 29-35.
[10]	Srivastava., Sharad., Rawat., Ajay., (2013). Quality Evaluation of Ayurvedic Crude Drug Daruharidra, Its Allied Species, and Commercial Samples from Herbal Drug Markets of India. Evidence-based complementary and alternative medicine (ECAM):472973.
[11]	Khare, C.P., (2004). Indian Herbal Remedies, Springer, New York: 98-100.
[12]	Ahmed M, Alamgeer, Sharif T, Zabta CHM & Akbar A., (2009). Effect ofBerberis lycium Royle on Lipid Profile in Alloxan Induced Diabetic Rabbits. Ethnobot Leaflets 13: 702-708.
[13]	Sharma, R.,(2003).Medicinal Plants of India An Encylopedia, Daya Publishing House, Delhi: 33-34.
[14]	Sood P, Modgil R, Sood M., (2010). Physico-chemical and nutritional evaluation of indigenous wild fruit Kasmal, Berberis lycium Royle. Indian. J. Nat. Prod.Res. 1(3): 362-366.
[15]	Shah, H., Shad, A. A., Perveen, S., Khattak, S. and Khattak, K. F., (2003). Physicochemical composition of wild medicinal plant Berberis lycium, J. Applied Sci., 3: 370-375.
[16]	Gulfraz, M., Arshad, M., Nayyer, N., Kanwal, N., and Nisar, U., (2004). Investigation for bioactive compounds of Berberis lycium Royle and Justicia adhatoda L., Ethnobot, Leaflets, 1: 51-62.
[17]	Srivastava, S., Vartica, R., Srivastava, M., Rawat, AKS., and Shanta, M., (2006). Estimation of heavy metals in different Berberis species and its market samples, Env., Monit, Assess., 116: 315-320.
[18]	Ahmed, M., Alamgeer, Sharif, T., Muhammad, ZCH., and Akbar. (2009). Effect of Berberis lycium Royle on lipid profile in alloxan induced diabetic rabbits, Ethnobotanical leaflets, 13: 702-708.
[19]	Miana, GA., (1973). Tertiary dihydroprotoberberine alkaloids of Berberis lycium. Phytochemistry, 12: 1822-3.
[20]	Datta, SC., Nigam, M.C., Virmani, OP., and Siddiqui, MS., (1976). Cold process for production of berberine hydrochloride from Berberis roots. Indian for, 139:204.
[21]	Leet JE., Hussain SF., Minard, RD., and Sharma, M., (1982). Sindamine, Punjabine, and Gilgitine: Three new seco-bisbenzylisoquinolines alkaloids. Heterocycles. 19:2355-60.
[22]	Chiang H., Hanssen CB., (1977). The Alkaloids. J. Org. Chem., 42: 3190-3192.
[23]	Shaista S., Kalim T., Naghmana R., Sidra N., B., Muhammad AS., and Mohammad S., (2013). Phytochemical and antioxidant studies of Berberis lycium. Pakistan journal of pharmaceutical sciences, Vol.26, No.6, November: 1165-1172.
[24]	Ahmad, M., Alamgeer, and Sharif, T. (2009). A potential adjunct to insulin Berberis lycium Diabet. Croatic 38(1): 13-18.
[25]	Asif, A., Kakub, G., Mehmood, S., Khunum, R., and Gulfraz, M., (2007). Wound Healing Activity of Root Extracts of Berberis lycium Royle in Rats. Phytother. Res. 21: 589-591.
[26]	Khan, M., Giessrgl, B., Vonach, C., Madlener, S., Prinz, S., Herbaceck, I., Hölzl, C., Bauer, S., Viola, K., Mikulits, W., Quereshi, RA., Knasmüller, S., Grusch, M., Kopp, B., and Krupitza, G., (2010). Berberine and a Berberis lycium extract inactivate Cdc25A and induce α tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis. Mut. Res. 683: 123-130.
[27]	Ahmad M., et al., (2009). “Effect of Berberis lycium Royle on lipid profile in alloxan induced diabetic rabbits”. Ethnobotanical leaflets 13, 702-708.
[28]	Gulfraz M., et al., (2007). “Anti-hyperglycemic effects of Berberis lyceum Royle in alloxan induced diabetic rats”. Diabetologia croatica 36.3): 49-54.
[29]	Khan MA., et al. (2008). “Hepatoprotective effects of Berberis lycium, Galium aparine and Pistacia ingtegerrima in carbon tetrachloride (CCl4)-treated rats”. Journal of Postgraduate Medical Institute 22.2, 91-94.
[30]	Ahmad M., et al. (2008). “Hepatoprotective effect of Berberis lycium (Royle) in hepatotoxic rabbits”. Gomal University journal of research: 24.
[31]	Lee, S. Lim, HJ. and Park, HJ., (2007). Berberine-induced LDLR up-regulation involves JNK pathway. Biochem. Biophys Res. Commun, 362: 853-7.
[32]	Tewary, DK., Bhardwaj, A., and Shanker, A., (2005). Pesticidal activities in five medicinal plants collected from mid hills of western Himalayas. Indus. Crop. Prod. 22: 241-247.
[33]	Khan, M., Giessrgl, B., Vonach, C., Madlener, S., Prinz, S., Herbaceck, I., Hölzl, C., Bauer, S., Viola, K., Mikulits, W., Quereshi, RA., Knasmüller, S., Grusch, M., Kopp, B., and Krupitza, G., (2010). Berberine and a Berberis lycium extract inactivate Cdc25A and induce α tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis. Mut. Res. 683: 123-130.
[34]	Singh M, Srivastava S., Rawat AKS., (2009). Antimicrobial Studies of Stem of Different Berberis Species. Nat Prod Sci. 15(2): 60-65.
[35]	Gupta R, Sharma M, Lakshamy R, Prabhakaran D & Reddy KS., (2009). Improved method of total antioxidant assay. Ind. J Biochem Biophysic 46: 126-129.
[36]	Sack, RB., and Froehlich, JL., (1982). Berberine inhibits intestinal secretary response of Vibrio cholera and Escherichia coli enterotoxins. Infect Immun., 35:471-5.
[37]	Manik Sharma, Javaid Iqbal, Som Kailash, Mohd Asgher, Mohd Younis, Jagrati Tripathi, Fakhar Shezad and Meraj Ud Din Hura. (2016). Multi-therapeutic activity of berberis lycium royle: a review. International Journal of Advanced research, 4(12), 2419-2431.
[38]	Lau, C.W., Yao, X.Q., Chen, Z.Y., KO, W.H., and Haung, Y., (2001). Cardiovascular actions of berberine. Cardiovasc. Drug. Rev., 19:234-244.
[39]	Kulkarni, SK. and Dhir, A., (2008). On the mechanism of antidepressant-like action of berberine chloride. Eur. J. Pharmacol, 589: 163-72.
[40]	Nyla Jabeen., et al. (2015). “Berberis lycium Royle (Royle, 1837): A Threatened Medicinal Plant and Its Biological Activities”. EC Agriculture 1.2: 100-108.
[41]	Singh A, Duggal S, Kaur N and Singh J., (2007). Oxidative Chemistry of Nitric Oxide, CRC Handbook of Free Radicals and Squadrito, Free. Radicals. J. Nat. Prod., 3: 64-75.
[42]	Kaneda, Y., Tanaka, T., and Saw, T. (1990). Effects of berberine, a plant alkaloid, on the growth of anaerobic protozoa in axenic culture. Tokai J. Exp., Clin. Med., 15: 417-23.
[43]	Choudhary, VP., Sabir, M. and Bhide, VN. (1972). Berberine in Giardiasis. Indian Pediarr, 9: 143-6.