American Journal of Medical Case Reports
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American Journal of Medical Case Reports. 2021, 9(7), 360-362
DOI: 10.12691/ajmcr-9-7-5
Open AccessCase Report

Vancomycin Induced Thrombocytopenia Complicating Permanent Pacemaker Placement: A Case Report

Chukwuemeka A. Umeh1, , Sabina Kumar1, John Carvalho1, Christina Arcuri1, Hycienth Ahaneku2, Krishna Pulumati3, Shivang Shah3, Austin Ma4 and Rakesh Gupta5

1Internal Medicine Department, Hemet Valley Medical Center, Hemet, California, USA

2Hematology and Oncology Department, Beaumont Health Hospital Royal Oak, Michigan USA

3Cardiology Department, Hemet Valley Medical Center, Hemet, California, USA

4Hematology and Oncology Department, Hemet Valley Medical Center, Hemet, California, USA

5Pulmonology and Critical Care Department, Hemet Valley Medical Center, Hemet, California, USA

Pub. Date: April 09, 2021

Cite this paper:
Chukwuemeka A. Umeh, Sabina Kumar, John Carvalho, Christina Arcuri, Hycienth Ahaneku, Krishna Pulumati, Shivang Shah, Austin Ma and Rakesh Gupta. Vancomycin Induced Thrombocytopenia Complicating Permanent Pacemaker Placement: A Case Report. American Journal of Medical Case Reports. 2021; 9(7):360-362. doi: 10.12691/ajmcr-9-7-5


Introduction: Vancomycin is widely used in patients with methicillin resistant staphylococcus aureus (MRSA) infections or with other infections unresponsive to other antibiotics. Vancomycin-related adverse effects, including nephrotoxicity, ototoxicity, red-man syndrome, and neutropenia have been reported. Vancomycin induced thrombocytopenia is a rare complication of vancomycin that many physicians are unaware of. When an acute decline in platelet count or bleeding occur in patients on vancomycin, vancomycin- induced thrombocytopenia should be considered. Case: We present a case of acute severe thrombocytopenia that occurred within 12 hours after vancomycin infusion in a patient that received permanent pacemaker placement. Vancomycin was discontinued and patient’s platelets returned to baseline five days after vancomycin was discontinued. Conclusion: This case report highlights the importance of physicians being aware of vancomycin induced thrombocytopenia, a rare but reversible complication of vancomycin, which if diagnosed early will lead to early discontinuation of vancomycin, early resolution of thrombocytopenia and reduced hospital stay.

vancomycin thrombocytopenia case report

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