American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
Open Access
Journal Browser
American Journal of Medical Case Reports. 2020, 8(4), 100-102
DOI: 10.12691/ajmcr-8-4-2
Open AccessArticle

Traumatic Brain Injury: a Case Report and Its Contribution to Understanding the Underlying Mechanisms - Alpha-Emitting Nanoparticulates Proven as Key

Florent Pirot1,

1Independent researcher, Plobannalec-Lesconil, France

Pub. Date: February 16, 2020

Cite this paper:
Florent Pirot. Traumatic Brain Injury: a Case Report and Its Contribution to Understanding the Underlying Mechanisms - Alpha-Emitting Nanoparticulates Proven as Key. American Journal of Medical Case Reports. 2020; 8(4):100-102. doi: 10.12691/ajmcr-8-4-2


This case report on a mild traumatic brain injury (self-diagnosis of the author on his own brain) leads to alpha-emitting nanoparticulates whose major contribution to TBI is confirmed by the extremely strong occurrence of TBIs in war veterans (with wideranging administrative data available to confirm the extremely strong typicality of the case). This allows a better and clearer understanding of the secondary injury events following TBI such as blood-brain barrier damage, mitochondria dysfunction and massive neuron death, of the various neurodegenerative disorders usually diagnosed following TBI such as chronic traumatic encephalopathy, chronic traumatic brain inflammation and indirect traumatic optic neuropathy, and of the risks of ischemic stroke following TBI.

traumatic brain injury chronic traumatic encephalopathy chronic traumatic brain inflammation neurodegenerative disorders indirect traumatic optic neuropathy diffuse axonal injury ischemic stroke concussion vision changes impulsivity apathy impaired memory impaired alertness anxiety depression ear ringing alpha-emitting nanoparticulates uranium thorium radium air pollution particulate matter plutonium depleted uranium

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Pirot F, “The link between salt and neurological disorders -the mediation of alpha-emitting nanoparticulates as simple explanation”, Porto Biomedical Journal, 4 (6). pe 55.
[2]  Miller AC, Rivas R, Tesoro L, Kovalenko G, Kovaric N, Pavlovic P, Brenner D, “Radiation exposure from depleted uranium: The radiation bystander effect”, Toxicology and Applied Pharmacology, 331 (15). 135-141. Sept 2017.
[3]  Azouvi P, Arnould A, Dromer E, Vallat-Azouvi C, “Neuropsychology of traumatic brain injury: An expert overview”, Revue Neurologique (Paris), 173 (7-8). 461-472. Jul - Aug 2017.
[4]  Pirot F, Alpha-emitting nanoparticulates, the forgotten pollutant, in From an Einstein Syndrome to the People, Editions Universitaires Européennes, 2019
[5]  Pavlovic D, Pekic S, Stojanovic M, Popovic V, “Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae”, Pituitary, 22 (3). 270-282. Jun 2019.
[6]  Garber BG, Rusu C, Zamorski MA, “Deployment-related mild traumatic brain injury, mental health problems, and post-concussive symptoms in Canadian Armed Forces personnel,” BMC Psychiatry, 20 (14). 325. Nov 2014.
[7]  Pirot F. “Contamination with Natural Radioactivity and Other Sources of Energy - the Explanation for Bose-Einstein Condensates, for the Creeping Behaviour of Helium and for the “Casimir Effect””, International Journal of Physics. 7 (3). 95-96. 2019.
[8]  Faden AI, Loane DJ, “Chronic Neurodegeneration after Traumatic Brain Injury: Alzheimer Disease, Chronic Traumatic Encephalopathy, or Persistent Neuroinflammation?”, Neurotherapeutics, 12 (1). 143-150. Jan 2015.
[9]  Collins JM, Woodhouse A, Bye N, Vickers J, King AE, Ziebell J, “Pathological links between traumatic brain injury and dementia: Australian pre-clinical research”, Journal of Neurotrauma, Feb 2020 (ahead of print).
[10]  van Eijck MM, Schoonman GG, van der Naalt J, de Vries J, Roks G, “Diffuse axonal injury after traumatic brain injury is a prognostic factor for functionl outcome: a systematic review and meta-analysis”, Brain Injury, 32 (4). 395 - 402. Jan 2018.
[11]  Dong W, Yang B, Wang L, Li B, Guo X, Zhang M, Jiang Z, Fu J, Pi J, Guan D, Zhao R, “Curcumin plays neuroprotective roles against traumatic brain injury partly via Nrf2 signaling”, Toxicology and Applied Pharmacology, 346 (1). 28-36. May 2018.
[12]  Siahaan AMP, Japardi I, Rambe AS, Indharty RS, Ichwan M, “Turmeric Extract Supplementation Reduces Tau Protein Level in Repetitive Traumatic Brain Injury Model”, Open Access Macedonian Journal of Medical Sciences, 6(11). 1953-1958. Nov 2018.
[13]  Farkhondeh T, Samarghandian S, Roshanravan B, Peivasteh-Roudsari L, “Impact of curcumin on traumatic brain injury and involved molecular signaling pathways”, Recent Patents on Food, Nutrition & Agriculture. Jun 2019.
[14]  Cai J, Xu D, Bai X, Pan R, Wang B, Sun S, Chen R, Sun J, Huang Y, “Curcumin mitigates cerebral vasospasm and early brain injury following subarachnoid hemorrhage via inhibiting cerebral inflammation”, Brain and Behaviour, 7(9). e00790. Sept 2017.
[15]  Sahin N, Kilic E, Ates N, Balcikanli Z, Orhan C, Tuzcu M, Sahin K, Juturu V, “Curcumin Plays Neuroprotection Activity by Modulation of Neurotrophic Factor BDNF, GAP-43 and GFAP in Mice with Traumatic Brain Injury (P06-043-19)”, Current Developments in Nutrition, 13(3). Suppl 1:nzz031.P06-043-19. Jun 2019.