American Journal of Infectious Diseases and Microbiology
ISSN (Print): 2328-4056 ISSN (Online): 2328-4064 Website: http://www.sciepub.com/journal/ajidm Editor-in-chief: Maysaa El Sayed Zaki
Open Access
Journal Browser
Go
American Journal of Infectious Diseases and Microbiology. 2015, 3(2), 74-76
DOI: 10.12691/ajidm-3-2-3
Open AccessCase Report

Plasmodium Vivax Malaria with Severe Thrombocytopenia and Varied Skin Manifestations: A Case Report

Tony Ete1, , Akash Roy1, Prasanta Kumar Bhattacharya1, Preeti Jane Picardo1, Md Jamil1, Ibandalin M Shangpliang1 and Hage Nobin1

1Department of General Medicine, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya

Pub. Date: March 13, 2015

Cite this paper:
Tony Ete, Akash Roy, Prasanta Kumar Bhattacharya, Preeti Jane Picardo, Md Jamil, Ibandalin M Shangpliang and Hage Nobin. Plasmodium Vivax Malaria with Severe Thrombocytopenia and Varied Skin Manifestations: A Case Report. American Journal of Infectious Diseases and Microbiology. 2015; 3(2):74-76. doi: 10.12691/ajidm-3-2-3

Abstract

Plasmodium vivax malaria is an endemic infection in India and is commonly associated with mild haematological abnormalities. Severe thrombocytopenia as well as purpuric skin manifestation are common in isolated falciparum and mixed falciparum/vivax malaria, but is very rare in isolated P.vivax infection. We hereby report a case of severe thrombocytopenia in a case of vivax malaria along with skin lesions presenting as purpura, ecchymosis and urticaria. Vivax malaria can no longer be considered as benign and atypical presentations with severe complications should be borne in the minds of physicians especially in a malaria endemic country like India.

Keywords:
Malaria Plasmodium vivax severe thrombocytopenia purpura ecchymosis

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Shiddapur, G. S., et al. “A case of Plasmodium vivax malaria with spontaneous subarachnoid hemorrhage and acute renal failure, severe thrombocytopenia, with anemia.” Medical Journal of Dr. DY Patil University 6.4 (2013): 482.
 
[2]  Bal, B. S., et al. “Haematological abnormalities in Plasmodium vivax malaria”. Journal of Indian Academy of Forensic Medicine. 34 (3) 2012: 236-238.
 
[3]  Vaishnani, Jignesh B. “Cutaneous findings in five cases of malaria.” Indian Journal of Dermatology, Venereology, and Leprology 77.1 (2011): 110.
 
[4]  Looareesuwan, S., et al. “Thrombocytopenia in malaria.” The Southeast Asian journal of tropical medicine and public health 23.1 (1992): 44-50.
 
[5]  Martelo, Orlando J., Marvin Smoller, and Thomas A. Saladin. “Malaria in American soldiers.” Archives of internal medicine 123.4 (1969): 383-387.
 
[6]  Horstmann, R. D., et al. “Malaria-induced thrombocytopenia.” Blut 42.3 (1981): 157-164.
 
[7]  Makkar, Ravinder Pal Singh, Surabhi Mukhopadhyay Amitabh Monga, and Ajay Kr Gupta. “Plasmodium vivax malaria presenting with severe thrombocytopenia.” Brazilian Journal of Infectious Diseases 6.5 (2002): 263-265.
 
[8]  Kaker A, Bloi S, Prakash V, Kaker S. “Profound thrombocytopenia in Plasmodium vivax Malaria”. Diag Microbial Infect Dis 1999; 35: 243-4.
 
[9]  Badlou, Bahram A., et al. “Platelet binding and phagocytosis by macrophages.” Transfusion 46.8 (2006): 1432-1443.
 
[10]  Zaki, Syed Ahmed, and Preeti Shanbag. “Plasmodium vivax malaria presenting with skin rash: a case report.” J Vector Borne Dis 48.4 (2011): 245-6.