Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: https://www.sciepub.com/journal/jfnr Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2020, 8(12), 722-729
DOI: 10.12691/jfnr-8-12-5
Open AccessArticle

Anti-inflammatory and Antinociceptive Activities of Decaffeinated Coffee

Maria Eliza de Castro Moreira1, Rosemary Gualberto Fonseca Alvarenga Pereira2, Daniele Ferreira Dias3, Claudinei Alves da Silva4, Thiago Corrêa de Souza5, Éderson D’Martin Costa6, Bárbara Pereira da Silva1, , Stella Maris da Silveira Duarte6, Alexandre Giusti-Paiva7 and Marcelo Henrique dos Santos8

1Faculdade Dinâmica do Vale do Piranga, Ponte Nova, Brazil

2Department of Food Science of Federal University of Lavras, Lavras, Brazil

3Institute of Chemistry of Federal University of Alfenas, Alfenas, Brazil

4Federal University of Jataí, CIEX, Jataí, Brazil

5Institute of Natural Sciences of Federal University of Alfenas, Alfenas, Brazil

6Faculty of Pharmaceutical Sciences of Federal University of Alfenas, Alfenas, Brazil

7Department of Biomedical Science of Federal University of Alfenas, Alfenas, Brazil

8Department of Chemistry of Federal University of Viçosa, Viçosa, Brazil

Pub. Date: December 08, 2020

Cite this paper:
Maria Eliza de Castro Moreira, Rosemary Gualberto Fonseca Alvarenga Pereira, Daniele Ferreira Dias, Claudinei Alves da Silva, Thiago Corrêa de Souza, Éderson D’Martin Costa, Bárbara Pereira da Silva, Stella Maris da Silveira Duarte, Alexandre Giusti-Paiva and Marcelo Henrique dos Santos. Anti-inflammatory and Antinociceptive Activities of Decaffeinated Coffee. Journal of Food and Nutrition Research. 2020; 8(12):722-729. doi: 10.12691/jfnr-8-12-5

Abstract

Epidemiological and experimental studies have found that the consumption of regular coffee has various health benefits. In the present study, we investigated the effect of decaffeinated coffee extracts on the inflammation process and found that aqueous extracts of green and roasted coffee have anti-inflammatory activity. The anti-inflammatory and antioxidant effects of aqueous extract of decaffeinated coffee (AD) and ethanol extract of decaffeinated coffee (ED) were evaluated in animal models using a DPPH radical scavenging test. In the formalin test, the extracts reduced licking activity in both late phases. The inhibitory values of oedema 3 h post-carrageenan indicated an anti-inflammatory effect. In the paw pressure test, the animals treated with extracts exhibited a reduction in the withdrawal threshold. These results provide evidence for the anti-inflammatory and antioxidant properties of decaffeinated coffee extracts that can be attributed to the potential of compounds present in coffee.

Keywords:
antioxidant activity chlorogenic acid coffea arabica hypernociception inflammation

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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