Chief Guest Editor

Yossi Cohen
Asaf Harofhe University Hospital
Email: yosefc@asaf.health.gov.il

Guest Editor

Odit Gutwein, MD.
Specializations in Internal Medicine and Hematololy, Principal Investigator in Several Phase II and Phase III Clinical Trials

After several decades of "stagnation" in the comprehension and management of the various subtypes of plasma cell disorders which are all sharing clonal proliferation of plasma cells with or without excretion of monoclonal proteins came since the late nineties of the past century a new era or "renaissance" in the field of this neoplasm which brought with it a tremendous progression in all areas from basic research and discovery of molecular events underlying the transformation through sophisticated diagnostic and prognostic tools up to an exciting development of first and second generation novel agents which already show benefit in terms of response, disease free survival and even overall survival. This special issue will concentrate on newer insights pertaining to the pathogenesis of plasma cell disorders, improved diagnostic tools, evaluation of current and future options of treatments as well as discussion on the place of stem cell transplantation in the overall management of patients. In addition, there will be emphasis on the mechanism of action of the novel agents in use and ways to improve them.

About the issue

The topics of this special issue include, but are not limited to: