Gelidium elegans Regulates Blood Glucose Homeostasis in ICR Mice

Jia Choi¹, Kui-Jin Kim¹, Eun-Jeong Koh¹, Young-Jin Seo¹ and Boo-Yong Lee^1,

¹Department of Food Science and Biotechnology, College of Life Science, CHA University, Seongnam, Kyonggi, Republic of Korea

Cite this paper:
Jia Choi, Kui-Jin Kim, Eun-Jeong Koh, Young-Jin Seo and Boo-Yong Lee. Gelidium elegans Regulates Blood Glucose Homeostasis in ICR Mice. Journal of Food and Nutrition Research. 2017; 5(4):274-280. doi: 10.12691/jfnr-5-4-9

Abstract

Gelidium elegans has been reported to improve metabolic function, but it has not been studied in non-obese mice with glucose tolerance. To evaluate the effect of Gelidium elegans (50 or 200 mg/kg doses) on glucose homeostasis, an oral glucose tolerance test (OGTT), oral maltose tolerance test (OMTT), and insulin tolerance test (ITT) were performed. The non-obese group of mice that was administered 200 mg/kg Gelidium elegans had significantly lowered blood glucose levels. By revealing that Gelidium elegans may improve glucose homeostasis, this study expands our understanding of the anti-diabetic effect of Gelidium elegans and its biological importance.

Keywords:
Gelidium elegans Gelidium amansii Hyperglycemia Diabetes Glucose absorption

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