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Murao, S., Nagano, H., Ogura, S., Nishino, T., Enzymatic synthesis of trehalose from maltose. Agricultural and biological chemistry 1985, 49, 2113-2118.

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Article

Gelidium elegans Regulates Blood Glucose Homeostasis in ICR Mice

1Department of Food Science and Biotechnology, College of Life Science, CHA University, Seongnam, Kyonggi, Republic of Korea


Journal of Food and Nutrition Research. 2017, Vol. 5 No. 4, 274-280
DOI: 10.12691/jfnr-5-4-9
Copyright © 2017 Science and Education Publishing

Cite this paper:
Jia Choi, Kui-Jin Kim, Eun-Jeong Koh, Young-Jin Seo, Boo-Yong Lee. Gelidium elegans Regulates Blood Glucose Homeostasis in ICR Mice. Journal of Food and Nutrition Research. 2017; 5(4):274-280. doi: 10.12691/jfnr-5-4-9.

Correspondence to: Boo-Yong  Lee, Department of Food Science and Biotechnology, College of Life Science, CHA University, Seongnam, Kyonggi, Republic of Korea. Email: bylee@cha.ac.kr

Abstract

Gelidium elegans has been reported to improve metabolic function, but it has not been studied in non-obese mice with glucose tolerance. To evaluate the effect of Gelidium elegans (50 or 200 mg/kg doses) on glucose homeostasis, an oral glucose tolerance test (OGTT), oral maltose tolerance test (OMTT), and insulin tolerance test (ITT) were performed. The non-obese group of mice that was administered 200 mg/kg Gelidium elegans had significantly lowered blood glucose levels. By revealing that Gelidium elegans may improve glucose homeostasis, this study expands our understanding of the anti-diabetic effect of Gelidium elegans and its biological importance.

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