Optimal Conditions for Extracting the Ginsenosides Rg3, Rg5, and Rk1 from Black Ginseng

Myo Jin Kwon¹, Kui-Jin Kim², Byung Wook Yang³, Boo-Yong Lee², Hyoung Chun Kim^4, and Sung Kwon Ko^{1, 3,}

¹Department of Oriental Medical Food & Nutrition, Semyung University, Jecheon, Republic of Korea

²Department of Food Science and Biotechnology, CHA University, Seongnam, Republic of Korea

³Ginseng Research Center, Koyeon, Jecheon, Republic of Korea

⁴College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea

Cite this paper:
Myo Jin Kwon, Kui-Jin Kim, Byung Wook Yang, Boo-Yong Lee, Hyoung Chun Kim and Sung Kwon Ko. Optimal Conditions for Extracting the Ginsenosides Rg3, Rg5, and Rk1 from Black Ginseng. Journal of Food and Nutrition Research. 2017; 5(3):176-179. doi: 10.12691/jfnr-5-3-6

Abstract

Ginseng is known to contain numerous ginsenosides, which exhibit beneficial health effects. In particular, ginsenoside Rg3, Rg5, and Rk1, derived from high temperature-processed ginseng, have higher bioactivities compared to other types of ginsenosides. In this study, we determined the optimal conditions for extraction of the valuable ginsenosides Rg3, Rg5, and Rk1 from black ginseng. Our results revealed that black ginseng extracted with 100°C distilled water for 0.5 hours and 6 hours yields large amounts of Rg3, Rg5, and Rk1 compared with other extraction times. We also found that protopanaxadiol (PPD) and protopanaxatriol (PPT) were also efficiently extracted from black ginseng with 100 °C distilled water at 0.5 hours and 6 hours and then rapidly degraded in a time-dependent manner. Therefore, we posit that short extraction times such as 0.5 hours and 6 hours might be optimal for isolation of the ginsenosides Rg3, Rg5, and Rk1 from black ginseng as opposed to longer extraction periods.

Keywords:
black ginseng ginsenoside prosapogenin protopanaxadiol protopanaxatriol Rg3 Rg5 Rk1

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