American Journal of Nanomaterials
ISSN (Print): 2372-3114 ISSN (Online): 2372-3122 Website: https://www.sciepub.com/journal/ajn Editor-in-chief: Apply for this position
Open Access
Journal Browser
Go
American Journal of Nanomaterials. 2013, 1(2), 27-30
DOI: 10.12691/ajn-1-2-3
Open AccessArticle

Sensing Capability of Fluorescent Sodium Salt of Amoxicillin

Abdul Hameed1, and Andaleeb Azam2

1Department of Chemistry, Kohat University of Science and Technology, Kohat, KPK, Pakistan

2Department of Chemistry, Shankar Campus, Abdul Wali Khan University Mardan, KPK, Pakistan

Pub. Date: November 10, 2013

Cite this paper:
Abdul Hameed and Andaleeb Azam. Sensing Capability of Fluorescent Sodium Salt of Amoxicillin. American Journal of Nanomaterials. 2013; 1(2):27-30. doi: 10.12691/ajn-1-2-3

Abstract

The capability of already available antibiotic drug ‘amoxicillin’ based on its fluorescent property has been explored. The fluorescent sodium salt of amoxicillin was used for the detection of heavy metals in aqueous solutions. It was found that Copper and Silver has a quenching effect on the fluorescence of amoxicillin. Cu2+ ions were detected in aqueous solution up to 1x10-7 M and Ag1+ ions up to 1x10-6 M. Hg2+ ions were also detected in aqueous samples but in high concentration.

Keywords:
sodium salt of amoxicillin fluorescence metallic sensing

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

Figures

Figure of 8

References:

[1]  A. X. Trautwein (Ed.), Bioinorganic Chemistry, Wiley VCH, Weinheim, 1997.
 
[2]  E. Merian (Ed.), Metals and Their Compounds in the Environment, VCH, Weinheim, 1991.
 
[3]  L. Sigg, H. Xue, Metal speciation: concepts, analysis and effects, in G. Bidoglio, W. Stumm (Eds.), Chemistry of Aquatic Systems: Local and Global Perspectives, Kluwer Academic Publishers, Dordrecht, 1994, p.153.
 
[4]  J. Szpunar, R. Lobinski, Fresenius J. Anal. Chem. 363 (1999) 550.
 
[5]  D. Radisky, J. Kaplan, J. Biol. Chem. 274 (1999) 4481.
 
[6]  D. Beyersmann, The significance of interactions in metal essentiality and toxicity, in :E. Merian (Ed.), Metals and Their Compounds in the Environment, VCH, Weinheim, 1991, p.491 Chapter I.10.
 
[7]  Brust, M.; Walker, M.; Bethell, D.; Schffrin, D. J.; Whyman, R., J. Chem. Soc., Chem. Commun. 1994, 801.
 
[8]  Templeton, A. C.; Wuelfing, M. P.; Murray, R. W., Acc. Chem. Res. 2000, 33, 27.
 
[9]  Zheng, J.; Zhang, C.; Dickson, R. M., J. Phys. Rev. Lett. 2004, 93, 077402.
 
[10]  Zheng, J.; Petty, J. T.; Dickson, R. M., J. Am. Chem. Soc. 2003, 125, 7780.
 
[11]  Schaaff, T. G.; Whetten, R. L., Giant Gold−Glutathione Cluster Compounds:  Intense Optical Activity in Metal-Based Transitions. The Journal of Physical Chemistry B 2000, 104 (12), 2630-2641.
 
[12]  Schaaff, T. G.; Knight, G.; Shafigullin, M. N.; Borkman, R. F.; Whetten, R. L., J. Phys. Chem. B 1998, 102, 10643.
 
[13]  Koneswaran, M.; Narayanaswamy, R., l-Cysteine-capped ZnS quantum dots based fluorescence sensor for Cu2+ ion. Sensors and Actuators B: Chemical 2009, 139 (1), 104-109.
 
[14]  Yang, W.; Gooding, J. J.; He, Z.; Li, Q.; Chen, G., Fast Colorimetric Detection of Copper Ions Using L-Cysteine Functionalized Gold Nanoparticles. Journal of Nanoscience and Nanotechnology 2007, 7 (2), 712-716.
 
[15]  Sugunan, A.; Thanachayanont, C.; Dutta, J.; Hilborn, J. G., Heavy-metal ion sensors using chitosan-capped gold nanoparticles. Science and Technology of Advanced Materials 2005, 6 (3-4), 335-340.
 
[16]  Liu, J.; Lu, Y., A DNAzyme Catalytic Beacon Sensor for Paramagnetic Cu2+ Ions in Aqueous Solution with High Sensitivity and Selectivity. Journal of the American Chemical Society 2007, 129 (32), 9838-9839.
 
[17]  Lan, G.-Y.; Huang, C.-C.; Chang, H.-T., Silver nanoclusters as fluorescent probes for selective and sensitive detection of copper ions. Chemical Communications 2010, 46 (8), 1257-1259.
 
[18]  Zheng, Y.; Orbulescu, J.; Ji, X.; Andreopoulos, F. M.; Pham, S. M.; Leblanc, R. M., Development of Fluorescent Film Sensors for the Detection of Divalent Copper. Journal of the American Chemical Society 2003, 125 (9), 2680-2686.
 
[19]  Hameed, A.; Islam, N. U.; Shah, M. R.; Kanwal, S., Facile one-pot synthesis of gold nanoparticles and their sensing protocol. Chemical Communications 2011, 47 (43), 11987-11989.
 
[20]  Bird, A. E., ANALYTICAL PROFILES OF DRUG SUBSTANCES AND EXCIPIENTS-VOLUME 23. Analytical Profiles of Drug Substances and Excipients 1994, 23, 1.
 
[21]  Brittain, H. G., Solid-state fluorescence of the trihydrate phases of ampicillin and amoxicillin. AAPS PharmSciTech 2005, 6 (3), 444-448.