Hyper Homocysteinemia Related Cerebral Venous Sinus Thrombosis –Presenting as Generalised Tonic-Clonic Seizure –A Case Report

Soumyabrata Roy Chaudhuri^1, , Deep Das², Subhayan Bhattacharya³, Subhankar Chakraborty⁴ and Kingshuk Bhattacharjee⁵

¹Senior Registrar, KPC Medical College, 1F, Raja Subodh Chandra Mullick Road Jadavpur, Kolkata West Bengal, India

²Consultant Neurologist, Woodlands Hospital, Alipore Road, Alipore, Kolkata, West Bengal, India

³Post Graduate Trainee, Dept. of Tropical Medicine, School of Tropical Medicine, Chittaranjan Avenue, Kolkata, West Bengal, India

⁴Consultant Internist, Anandalok Hospital, D.K.7/3Salt lake City, Kolkata, West Bengal, India

⁵Assistant Manager, Medical Services, Biocon LTD, Kolkata

Cite this paper:
Soumyabrata Roy Chaudhuri, Deep Das, Subhayan Bhattacharya, Subhankar Chakraborty and Kingshuk Bhattacharjee. Hyper Homocysteinemia Related Cerebral Venous Sinus Thrombosis –Presenting as Generalised Tonic-Clonic Seizure –A Case Report. International Journal of Clinical and Experimental Neurology. 2017; 5(1):5-8. doi: 10.12691/ijcen-5-1-2

Abstract

Cerebral venous sinus thrombosis (CVST) is a neuromuscular disorder with protean manifestation requiring a high index of suspicion. Early diagnosis is sometimes lifesaving. It is particularly challenging is to establish an accurate etiology as it guides the clinician for long term thrombo-prophylaxis. We report a young female with no conventional risk factors for CVST, who presented with headache, generalised seizures and prolonged loss of consciousness. Her work-up revealed an elevated serum homocysteine level which might be a possible causative association in the etiopathogenesis of this neuromuscular condition.

Keywords:
hyperhomocysteinemia young female CVST

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