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Stam J. Thrombosis of the cerebral veins and sinuses. N Engl J Med 2005; 352:1791-8.

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Article

Hyper Homocysteinemia Related Cerebral Venous Sinus Thrombosis –Presenting as Generalised Tonic-Clonic Seizure –A Case Report

1Senior Registrar, KPC Medical College, 1F, Raja Subodh Chandra Mullick Road Jadavpur, Kolkata West Bengal, India

2Consultant Neurologist, Woodlands Hospital, Alipore Road, Alipore, Kolkata, West Bengal, India

3Post Graduate Trainee, Dept. of Tropical Medicine, School of Tropical Medicine, Chittaranjan Avenue, Kolkata, West Bengal, India

4Consultant Internist, Anandalok Hospital, D.K.7/3Salt lake City, Kolkata, West Bengal, India

5Assistant Manager, Medical Services, Biocon LTD, Kolkata


International Journal of Clinical and Experimental Neurology. 2017, Vol. 5 No. 1, 5-8
DOI: 10.12691/ijcen-5-1-2
Copyright © 2017 Science and Education Publishing

Cite this paper:
Soumyabrata Roy Chaudhuri, Deep Das, Subhayan Bhattacharya, Subhankar Chakraborty, Kingshuk Bhattacharjee. Hyper Homocysteinemia Related Cerebral Venous Sinus Thrombosis –Presenting as Generalised Tonic-Clonic Seizure –A Case Report. International Journal of Clinical and Experimental Neurology. 2017; 5(1):5-8. doi: 10.12691/ijcen-5-1-2.

Correspondence to: Soumyabrata  Roy Chaudhuri, Senior Registrar, KPC Medical College, 1F, Raja Subodh Chandra Mullick Road Jadavpur, Kolkata West Bengal, India. Email: soumya.academics@gmail.com

Abstract

Cerebral venous sinus thrombosis (CVST) is a neuromuscular disorder with protean manifestation requiring a high index of suspicion. Early diagnosis is sometimes lifesaving. It is particularly challenging is to establish an accurate etiology as it guides the clinician for long term thrombo-prophylaxis. We report a young female with no conventional risk factors for CVST, who presented with headache, generalised seizures and prolonged loss of consciousness. Her work-up revealed an elevated serum homocysteine level which might be a possible causative association in the etiopathogenesis of this neuromuscular condition.

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