Journal of Environment Pollution and Human Health
ISSN (Print): 2334-3397 ISSN (Online): 2334-3494 Website: https://www.sciepub.com/journal/jephh Editor-in-chief: Dibyendu Banerjee
Open Access
Journal Browser
Go
Journal of Environment Pollution and Human Health. 2026, 14(1), 1-7
DOI: 10.12691/jephh-14-1-1
Open AccessArticle

Risk Assessment Related to Metallic Trace Elements Present in Toothpaste Sold in Supermarkets in Abidjan (Côte D’Ivoire)

SANGARE Naminata SOUMAHORO1, , ZRAN Vanh Eric-Simon1, GNONSORO Urbain Paul2 and KOFFI Koffi Didier1

1Laboratoire de Constitution et de Réaction de la Matière, Université Félix Houphouët Boigny, 22 BP 582 Abidjan, Côte d’Ivoire

2Département des Sciences et Techniques, Université Alassane Ouattara, BP V 18 Bouaké, Côte d’Ivoire

Pub. Date: February 24, 2026

Cite this paper:
SANGARE Naminata SOUMAHORO, ZRAN Vanh Eric-Simon, GNONSORO Urbain Paul and KOFFI Koffi Didier. Risk Assessment Related to Metallic Trace Elements Present in Toothpaste Sold in Supermarkets in Abidjan (Côte D’Ivoire). Journal of Environment Pollution and Human Health. 2026; 14(1):1-7. doi: 10.12691/jephh-14-1-1

Abstract

Toothpaste, a widely used oral hygiene product, can constitute a pathway for exposure to metallic trace elements (ETM) due to their composition and manufacturing processes. Although these products are subject to regulations, the presence of toxic ETMs (Cd, Pb, Ni, Fe et Zn) remains a concern, particularly in developing countries where quality controls may be limited. This study aims to quantify the concentrations of Cd, Pb, Ni, Fe, and Zn in toothpastes sold in Abidjan, and assess the health risks associated with their use by ingestion and dermal route. Five brands of toothpastes were selected based on their popularity. Twenty-five samples were analyzed by X-ray fluorescence spectrometry (MESA-50). Non-carcinogenic and carcinogenic risks were calculated according to USEPA protocols. Results showed that average Zn concentrations (0.004–0.937 mg/kg) is higher in 60% of samples. Cd had high levels in P3 (0.055 mg/kg). Dermatological non-carcinogenic risk calculations QD values < 1 for all different toothpastes, thus would not constitute a potential hazard to the consumer. However, hazard quotients (HQs) by ingestion were >1 for Cd (38.99), Ni (1.16), and Pb (5.90), indicating a potential toxic risk. Carcinogenic risks (CR) were particularly high for Cd (253.4. 10-6), exceeding the acceptable threshold (1 × 10-6). This study reveals significant contamination by certain TMEs, particularly Zn and Cd, in toothpastes marketed in Abidjan. Although cutaneous risks are negligible, chronic ingestion could lead to cumulative toxic effects. Strengthened quality controls and awareness campaigns are recommended.

Keywords:
Trace metal elements Toothpastes Risk assessment X-ray fluorescence Population health

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Al-Saleh, I., Al-Enazi, S., Shinwari, N., “Assessment of lead in cosmetic products”, Regulatory Toxicology and Pharmacology: RTP, 54(2), 105–113. 2009.
 
[2]  Jaishankar, M., Tseten, T., Anbalagan, N., Mathew, B. B., & Beeregowda, K. N., “Toxicity, mechanism and health effects of some heavy metals”, Interdisciplinary Toxicology, 7(2), 60–72. 2014.
 
[3]  Borysewicz-Lewicka, M., Opydo-Szymaczek, J., “Fluoride in Polish Drinking Water and the Possible Risk of Dental Fluorosis”, Polish Journal of Environmental Studies, 25(1), 9–15. 2016.
 
[4]  Rebelo, F.M., Caldas, E.D., “Arsenic, lead, mercury and cadmium: Toxicity, levels in breast milk and the risks for breastfed infants”, Environmental Research, 151, 671–688. 2016.
 
[5]  U.S. Department of Health and Human Services/Agency for Toxic Substances Disease Registry (ATSDR), “Toxicological Profile for Lead” 2020.
 
[6]  World Health Organization, Guidelines for drinking-water quality (4th ed). World Health Organization, 2011. https:// iris.who.int/handle/10665/44584.
 
[7]  Huet A., Marie-Cousin A., Sixou J.L., “Fluoride in children in 2010”, Dental Information, 63–70. 2010.
 
[8]  Zolaly, M.A., Hanafi, M.I., Shawky, N., El-Harbi, K., Mohamadin, A.M. (2012). “Association between blood lead levels and environmental exposure among Saudi schoolchildren in certain districts of Al-Madinah”, International Journal of General Medicine, 5, 355–364. 2012.
 
[9]  Ministry of Health Decree No. 94-014/PRES/PM/MICM/MFPL OF JANUARY 6, 1994.
 
[10]  Means, B., “Risk-assessment guidance for Superfund”. Volume 1. Human Health Evaluation Manual. Part A. Interim report (Final). Environmental Protection Agency, Washington, DC (USA). Office of Solid Waste and Emergency Response. 1989. PB-90-155581/XAB; EPA-540/1-89/002.
 
[11]  Kobayashi, C.A.N., Belini, M.R., Italiani, F.M., Pauleto, A.R.C., Julianelli de Arau´ jo, J., Tessarolli, V., Grizzo, L.T., Pessan, J.P., Machado, M.A.A.M., Buzalaf, M.A.R., “Factors influencing fluoride ingestion”, Journal of Applied Oral Science, 19(1).2011.
 
[12]  Richards, A., Banting, D.W., “Fluoride toothpastes”. In: Fejerskov O, Ekstrand J, Burt BA, (eds). Fluoride in dentistry, 2nd ed. Copenhagen: Munksgaard 1996; 328–46.
 
[13]  Sun, F., Chen, S., Zhang, H., & Zhang, X., “Health risk assessment of heavy metals in the surface water of Taihu Lake, China”, Environmental Toxicology and Pharmacology, 24(2), 151-157. 2007.
 
[14]  Huang, M., Zhou, S., Sun, B., Zhao, Q., “Heavy metals in wheat grain: Assessment of potential health risks for populations in Kunshan, China”, Science of The Total Environment, 405(1), 54–61. 2008.
 
[15]  Non-cancer Risks Associated With Heavy Metal Exposures from Street Foods: Evaluation of Roasted Meats in an Urban Setting”, Journal of Environment Pollution and Human Health, 3(2). 20150Article 2.
 
[16]  Giri, A., Bharti, V. K., Kalia, S., Kumar, B., Chaurasia, O. P., “Health Risk Assessment of Heavy Metals Through Cow Milk Consumption in Trans-Himalayan High-Altitude Region”, Biological Trace Element Research, 199(12), 4572–4581. 2021.
 
[17]  Storelli, A., Barone, G., Dambrosio, A., Garofalo, R., Busco, A., Storelli, M. M., “Occurrence of trace metals in fish from South Italy: Assessment risk to consumer’s health”, Journal of Food Composition and Analysis, 90, 103487.2020.
 
[18]  Cobbina, J., “Non-cancer risk assessment from exposure to mercury (Hg), cadmium (Cd), arsenic (As), copper (Cu), and lead (Pb) in boreholes and surface water in Tinga, in the Bole-Bamboi District, Ghana”, Journal of Toxicology and Environmental Health Sciences, 5(2), 29-36.2013.
 
[19]  U.S. Environmental Protection Agency & Office of Emergency and Remedial Response, “Risk Assessment Guidance for Superfund”. 1989. https:// www.epa.gov/ risk/risk-assessment-guidance-superfund-rags-part.
 
[20]  Brandy, M.L., Peggy, R., “Toothpastes. MiDiFABs”, 5.2006. http:// midifab. free.fr/MiDiFABs/archive/v5/MidiFABs_v5_p87.pdf.
 
[21]  Tepanosyan, G., Maghakyan, N., Sahakyan, L., Saghatelyan, A., “Heavy metals pollution levels and children health risk assessment of Yerevan kindergartens soils”, Ecotoxicology and Environmental Safety, 142, 257–265. 2017.
 
[22]  European Parliament and Council,“Regulation (EC) No 1223/2009 on cosmetic products”, Official Journal of the European Union, L 342, 59–209.2009.
 
[23]  International Organization for Standardization (ISO 11609:2017), “Dentistry — Toothpaste — Requirements, test methods and marking”.2017.
 
[24]  Orisakwe, O.E., Okolo, K.O., Igweze,Z .N., Ajaezi, G.C., Udowelle, N.A., “potential hazards of toxic metals found in toothpastes commonly used in Nigeria”, Pub Med Rocz Panstw Zakl Hig.,67(2), 197-204. 2016. PMID: 27289516.
 
[25]  Rozencweig, D., “Fluoride toothpastes”. In MunksgaardTextbook. Fluoride in dentistry. 2 ndeed. Copenhagen, 69-87.1996.
 
[26]  Brandy, M.L., Robert, P., “Toothpastes”. MIDIFABS 5, 87-96.2006.
 
[27]  Kibret, M., Kim, H., Lee, T. H., “Microbial removal of heavy metals from contaminated soil”. Journal of Environmental Science and Health, Part A, 43(3), 302-308. 2008.
 
[28]  Munyonga, M., Muchenje, V., Dzama, K., Effect of packaging materials on the migration of heavy metals into foodstuffs. Journal of Food Science and Technology, 49(6), 742-746.2012.
 
[29]  Ali, M., Ahmed, S., Ansari, M.A., Irfan, S., “Heavy Metals Detection and Risk Assessment in Selected Toothpastes”, International Journal of Scientific Research in Environmental Sciences, 1(8), 173-177.2013
 
[30]  Amartey, E.O., Asumadu-Sakyi, A.B., Adjei, C.A., Quashie, F.K., Bentil, N.O., “Determination of Heavy Metals in Toothpaste Commonly Used in Ghana”, Journal of Chemical and Pharmaceutical Research, 3(6), 1-7.2011.
 
[31]  Kane A.W., Faye B., Sarr M., Cisse D., Diop O., Diallo B., “Oral hygiene habits and dental caries status of students. Survey of 150 students in university residences in Dakar—Senegal”. Odontostomatologie tropicale, 93, 20. 2001.
 
[32]  Baranowska I., Barchański L., Bąk M., Smolec B., Mzyk Z., “X-ray fluorescence spectrometry in multielemental analysis of hair and teeth”, Polish Journal of Environmental Studies;13:639-646.2004.
 
[33]  Shirasawa K., Ektessabi A., Koizumi A., Azechi M., Sie S., “Assessment of the environment using synchrotron radiation micro-beams”, Journal of Electron Spectroscopy and Related Phenomena, 137–140, 827–830. 2004.
 
[34]  Muster, D., “Oral medical therapeutics: Means and methods: Means And Methods”, Elsevier Masson. 2004.
 
[35]  Addy, M., “Tooth brushing, tooth wear, and dentine hypersensitivity—Are they associated”, International Dental Journal, 55(4 Suppl 1), 261–267.
 
[36]  Sainio, E.L., Kanerva, L., “Contact allergens in toothpastes and a review of their hypersensitivity”, Contact Dermatitis, 33(2), 100–105.
 
[37]  Maffini, M. V., Neltner, T. G., Vogel, S., “We are what we eat: Regulatory gaps in the United States that put our health at risk”, PLoS Biology, 15(12), e2003578. 2017.