Indole-3-carbinol: A Promising Hope for Cancer Therapy

Ahmed M. Kabel^{1, 2,} , Eman A. Alharthi³, Rana K. Alshehri³ and Afnan S. Alghamdi³

¹Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, KSA

²Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt

³Pharm D, College of Pharmacy, Taif University, Taif, KSA

Cite this paper:
Ahmed M. Kabel, Eman A. Alharthi, Rana K. Alshehri and Afnan S. Alghamdi. Indole-3-carbinol: A Promising Hope for Cancer Therapy. Journal of Cancer Research and Treatment. 2018; 6(1):25-27. doi: 10.12691/jcrt-6-1-5

Abstract

Indole-3-carbinol (I3C) is a natural agent found in high amounts in cruciferous vegetables and is also available as dietary supplements. It is considered as a promising agent for the ongoing medical research due to its possible antioxidant, anti-inflammatory, anti-tumor, antiapoptotic and anti-atherogenic properties. Recent studies are directed towards assessment of the possible effects of I3C on various body organs including the heart, liver, kidney and the endocrine system. This mini-review sheds light on the different properties of I3C that make it a promising therapeutic agent for a wide variety of human diseases including cancer.

Keywords:
cruciferous vegetables indole-3-carbinol natural agent cancer

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