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Al-Harthi SE, Alarabi OM, Ramadan WS, Alaama MN, Al-Kreathy HM, Damanhouri ZA, Khan LM, Osman AM. Amelioration of doxorubicin induced cardiotoxicity by resveratrol. Mol Med Rep 2014; 10: 1455-60.

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Article

Indole-3-carbinol: A Promising Hope for Cancer Therapy

1Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, KSA

2Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt

3Pharm D, College of Pharmacy, Taif University, Taif, KSA


Journal of Cancer Research and Treatment. 2018, Vol. 6 No. 1, 25-27
DOI: 10.12691/jcrt-6-1-5
Copyright © 2018 Science and Education Publishing

Cite this paper:
Ahmed M. Kabel, Eman A. Alharthi, Rana K. Alshehri, Afnan S. Alghamdi. Indole-3-carbinol: A Promising Hope for Cancer Therapy. Journal of Cancer Research and Treatment. 2018; 6(1):25-27. doi: 10.12691/jcrt-6-1-5.

Correspondence to: Ahmed  M. Kabel, Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, KSA. Email: drakabel@gmail.com

Abstract

Indole-3-carbinol (I3C) is a natural agent found in high amounts in cruciferous vegetables and is also available as dietary supplements. It is considered as a promising agent for the ongoing medical research due to its possible antioxidant, anti-inflammatory, anti-tumor, antiapoptotic and anti-atherogenic properties. Recent studies are directed towards assessment of the possible effects of I3C on various body organs including the heart, liver, kidney and the endocrine system. This mini-review sheds light on the different properties of I3C that make it a promising therapeutic agent for a wide variety of human diseases including cancer.

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