Prothrombin Time, Activated partial Thromboplastin Time and Platelets Count in Pregnant Females and Postpartum Period with Deep Venous Thrombosis

Huda I. Babiker¹, Hiba A. Awooda² and Sana E. Abdalla^3,

¹Department of Hematology, Faculty of Medical Laboratory, Alneelain University, Khartoum, Sudan

²Department of Physiology, Faculty of Medicine and Heath Sciences, Alneelain University, Khartoum, Sudan

³Medical Researches, Faculty of Medicine Center, Alneelin University, Khartoum, Sudan

Cite this paper:
Huda I. Babiker, Hiba A. Awooda and Sana E. Abdalla. Prothrombin Time, Activated partial Thromboplastin Time and Platelets Count in Pregnant Females and Postpartum Period with Deep Venous Thrombosis. International Journal of Hematological Disorders. 2014; 1(1):41-44. doi: 10.12691/ijhd-1-1-8

Abstract

Background: Venous thromboembolism is one of the major causes of maternal morbidity and mortality, the aims of this work was to determine the levels of (Prothrombin time (PT), activated partial thromboplastin time (APTT) and platelets count (PLts)) in pregnant and postpartum when affected with deep venous thrombosis (DVT). Methods: Fifty female of child bearing age (15-45) years presented with signs of (DVT) either during pregnancy or postpartum period were investigated for PT, APTT and Plts count and fifty other pregnant and postpartum presented without signs of DVT were included as control groups, the patients females and control completed questionnaire of personal data and clinical history such as age, case study (pregnant or postpartum), usage of contraceptive pills and family history of DVT and number of pregnancies. The automated method used to measure PT, APTT, coagulomator and PLTs count using (sysmex K21). Results: Distribution of bleeding profile according to age groups showed that, mean of platelets count was higher (286.7) in young age (15-25 yrs.), PT was prolonged in vast majority of case group (90%), while it was normal in 10% of study population. APTT was prolonged in 62% of patients, mostly higher in third trimester with percentage of 69.4%. Platelets count found normal in vast majority of patients in all 3 trimesters. Conclusion: Normal platelet level where found in both control and case, while PT is significally prolonged in the case (P=0.00). While APTT is also prolonged in the case group; but not statistically significant with the control.

Keywords:
Prothrombin Thromboplastin Platelets thrombosis

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