Nutrition in Celiac Disease

Pavel Kohout^1,

¹Department of Internal Medicine, Thomayer´s Hospital, Prague, Czech Republic

Cite this paper:
Pavel Kohout. Nutrition in Celiac Disease. International Journal of Celiac Disease. 2014; 2(3):115-117. doi: 10.12691/ijcd-2-3-2

Abstract

Nutrition plays a key role in patients with celiac disease. Gluten-free diet is main therapeutic option despite of new possibilities keeping the intestinal barrier, modulation of gut microbiome or extraction of gluten from the diet. The prevention of formation the autoimmune reaction against gluten in genetically predisposed patients is the addition of small amount of gluten-rich food during breastfeeding between 4th and 7th months of life. The possible prevention at a later age could include the keeping of gluten-free diet during stress-induced damage of intestinal barrier and/or the influence of gut microbiom using probiotics.Gluten-free diet become to be new phenomenon, new strategy for non-celiac population despite of absency of proven benefits for them. There are defined new clinical entities of gluten intolerance, especially non-celiac gluten sensitivity, but its differentiation from irritable bowel syndrome is very difficult. This issue will require further research.

Keywords:
celiac disease gluten-free diet gut microbiome gluten sensitivity probiotics non-celiac gluten sensitivity intestinal barrier

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References:

[1]	Lundin KE, Sollid LM. Advances in cœliac disease. Curr Opin Gastroenterol. 2014; 30: 154-162.
[2]	Olives JP. When should we introduce gluten into the feeding of the new-born babies? Arch Pediatr 2010; 17: 5: S 199-203.
[3]	Revised criteria for diagnosis of celiac disease. Report of Working Group of European Society of Gastroenterology and Nutrition. Arch Dis Child 1990; 65: 909-911.
[4]	Hill ID, Dirks MH, Liptak GS et al. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 2005; 40: 1-19.
[5]	Auricchio R, Granata V, Borrelli M, Troncone R; Italian Society for Pediatric Gastroenterology Hepatology and Nutrition (SIGENP). Italian paediatricians' approach to coeliac disease diagnosis. J Pediatr Gastroenterol Nutr 2009; 49: 374-376.
[6]	Hill PG, Holmes GK. Coeliac disease: a biopsy is not always necessary for diagnosis. Aliment Pharmacol Ther 2008; 27:572-577.
[7]	Hill ID, Horvath K. Nonbiopsy diagnosis of celiac disease: are we nearly there yet? J Pediatr Gastroenterol Nutr 2012; 54: 310-311.
[8]	Lamireau T, Clouzeau H. What can confirm the celiac disease diagnosis? Arch Pediatr 2008; 15: 504-505.
[9]	Garnier-Lengliné H, Brousse N, Candon S et al. Have serological tests changed the face of childhood coeliac disease? A retrospective cohort study. BMJ Open 2012; 2. e 001385
[10]	Clouzeau-Girard H, Rebouissoux L, Taupin et al. HLA-DQ genotyping combined with serological markers for the diagnosis of celiac disease: is intestinal biopsy still mandatory? J Pediatr Gastroenterol Nutr 2011; 52: 729-733.
[11]	Ribes-Koninckx C, Mearin ML, Korponay-Szabó IR et al. ESPGHAN Working Group on Coeliac Disease Diagnosis. Coeliac disease diagnosis: ESPGHAN 1990 criteria or need for a change? Results of a questionnaire. J Pediatr Gastroenterol Nutr 2012; 54: 15-19.
[12]	Brusca I, Carroccio A, Tonutti E et al. The old and new tests for celiac disease: which is the best test combination to diagnose celiac disease in pediatric patients? Clin Chem Lab Med 2011; 50: 111-117.
[13]	Husby S, Koletzko S, Korponay-Szabo IR et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012; 54: 136-160.
[14]	Olives JP. Should the whole population be screened for celiac disease? Pathol Biol 2011. doi 10.1016/j.patbio.2011. 03 009.
[15]	Kurppa K, Salminiemi J, Ukkola A et al. Utility of the new ESPGHAN criteria for the diagnosis of celiac disease in at-risk groups. J Pediatr Gastroenterol Nutr 2012; 54: 387-391.
[16]	Klapp G, Masip E, Bolonio M et al. Celiac disease: the new proposed ESPGHAN diagnostic criteria do work well in a selected population. J Pediatr Gastroenterol Nutr 2013; 56: 251-256.