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Biomedicine and Biotechnology. 2022, 7(1), 6-22
DOI: 10.12691/bb-7-1-2
Open AccessReview Article

The Principle, Types, and Applications of Mass Spectrometry: A Comprehensive Review

Sabitha Vadakedath1, , Venkataramana Kandi1, Vikram Godishala2, Venkata Bharat Kumar Pinnelli3, Samar Sami Alkafaas4 and Sara Sami EIkafas5

1Prathima Institute of Medical Sciences, Telangana, India

2Vaagdevi Degree and PG College, Telangana, India

3Vydehi Institute of Medical Sciences and Research Center, Bengaluru, India

4Tanta University, Tanta, Egypt

5Menofia University, Menofia, Egypt

Pub. Date: October 22, 2022
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Cite this paper:
Sabitha Vadakedath, Venkataramana Kandi, Vikram Godishala, Venkata Bharat Kumar Pinnelli, Samar Sami Alkafaas and Sara Sami EIkafas. The Principle, Types, and Applications of Mass Spectrometry: A Comprehensive Review. Biomedicine and Biotechnology. 2022; 7(1):6-22. doi: 10.12691/bb-7-1-2

Abstract

Mass spectrometry (MS) is a technique wherein chemical substances are identified in biological and non-biological material. It uses electric and magnetic fields to sort out gaseous ions based on their mass-to-charge ratios. The MS is a technique that uses a mass spectrometer and mass spectrograph as instruments that work by using electric/magnetic fields, and photographic techniques/non-electric means, respectively. The applications of MS include the identification of gases present in the atmosphere. However, applications of MS in medicine assume increased significance owing to the benefit it does in the management of patients, and public health as a whole. Several MS-based clinical diagnostic devices are already available, and many others are in the pipeline. This review presents a comprehensive analysis of the basics of MS, types of MS-based instruments, and their applications.

Keywords:
mass spectrometry chemical substances biological techniques medicine mass spectrograph patients public health diagnostic devices

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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