Screening of Medicinal Plants Native To Kano and Jigawa States of Northern Nigeria, Using Artemia Cysts (Brine Shrimp Test)

O. A. ADOUM^1,

¹Department of Pure and Industrial Chemistry, Bayero University, Kano Nigeria

Cite this paper:
O. A. ADOUM. Screening of Medicinal Plants Native To Kano and Jigawa States of Northern Nigeria, Using Artemia Cysts (Brine Shrimp Test). American Journal of Pharmacological Sciences. 2016; 4(1):7-10. doi: 10.12691/ajps-4-1-2

Abstract

Eleven plant species belonging to 9 families were selected in this study on the basis of their uses in Hausa folk medicine. Extracts prepared from the plans were solvent partitioned and screened for activity in the brine shrimp (Artemia cysts) lethality test (BST). All the leaves extracts of Cassia singueana exhibited very high toxicity in brine shrimp test (BST) at LC₅₀ values less than 11µg/ml. Some extracts of Commiphra kerstingi, Jatropha curcas, Erythrina senegalensis and Securidaca longepedunculata have showed remarkable toxicity in BST at LC₅₀ values range between 4.5 - 367 µg/ml. Only Diospyros mespiliformis (Ebenaceae) showed very low brine shrimp lethality at LC₅₀ > 1000 µg/ml. The lethal concentration (LC₅₀) were determined at 95% confidence intervals by analyzing the data on a computer loaded with "Finney Programme."

Keywords:
artemia cysts Brine shrimp test toxicity Jigawa Kano

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