Ichnocarpus frutescens Stem Extract: Effect of Different Concentrations of Solvent on Total Phenol Content, Total Flavonoid Content and on Its Antioxidant Activity

Babita Aggarwal¹, Antariksh Katara², Harsh Raghav³, Santosh Kumar Verma⁴ and Ajeet^4,

¹School of Pharmacy, Vishveshwarya Group of Institutions, Greater Noida, India

²Agri, Food and Life Sciences Lab, CEG Test House and Research Centre Pvt. Ltd., Jaipur, Rajasthan

³Department of Pharmaceutics, HR Institute of Pharmacy, Ghaziabad, India

⁴Faculty of Pharmaceutical Sciences, Motherhood University, Roorkee, India

Cite this paper:
Babita Aggarwal, Antariksh Katara, Harsh Raghav, Santosh Kumar Verma and Ajeet. Ichnocarpus frutescens Stem Extract: Effect of Different Concentrations of Solvent on Total Phenol Content, Total Flavonoid Content and on Its Antioxidant Activity. American Journal of Pharmacological Sciences. 2019; 7(1):1-4. doi: 10.12691/ajps-7-1-1

Abstract

Free radicals formed from reactive oxygen species can oxidize biomolecules leading to tissue injury and cell death. Oxidative stress is generated by imbalance between reactive oxygen species and antioxidants. Hence, to overcome this problem, an attempt has been drawn by studying Ichnocarpus frutescens stem extract. In order to study it we have gone through total phenolic content, total flavonoid content as quantification of secondary metabolite. As far as antioxidant activity concerns, DPPH radical scavenging, reducing power assay and total antioxidant activity were performed and analyzed. During this analysis, we have found that 80% ethanol showed maximum activity as compared to 50% and 95% ethanolic extract of Ichnocarpus frutescens stem.

Keywords:
total phenolic content total flavonoid content free radical oxidative stress reducing power radical scavenging

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