Association Between Il17a G197a Polymorphism and Rosacea in the Uzbek Population

Yakubov A.A.¹, Sabirov U.Yu¹ and Boboev K.T^2,

¹Republican Specialized Scientific and Practical Medical Center of Dermatovenereology and Cosmetology, Tashkent, Uzbekistan

²Republican specialized scientific-practical medical center of hematology

Cite this paper:
Yakubov A.A., Sabirov U.Yu and Boboev K.T. Association Between Il17a G197a Polymorphism and Rosacea in the Uzbek Population. American Journal of Medical Sciences and Medicine. 2025; 13(3):40-43. doi: 10.12691/ajmsm-13-3-3

Abstract

Rosacea is a chronic, progressive, inflammatory disease manifested by recurrent course, erythema, telangiectasia, papules or pustules on the central part of the face. Currently, the etiology and pathogenesis of rosacea are not fully understood, and treatment requires improvements. Currently, there is a growing interest in the entire interleukin family - in the pathophysiology of many human diseases, including skin diseases. Several studies have been devoted to the study of IL-17 in rosacea patients, but the results of these studies are contradictory to each other. With this in mind, this article will focus on the key role of interleukin 17 (IL-17) in the development and progression of the disease based on our own research conducted.

Keywords:
rosacea IL17A gene polymorphism clinical stages of rosacea IL17A genotypes Uzbek population

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