A Rare Clinical Manifestation of Piebaldism: Case Report and Review of Literature

Professor Khitam Al-Refu^1, , Heba Al-lala² and Hiba Harbi³

¹Faculty of Medicine, Muta University

²School of Medicine, the University of Jordan, Amman 11418, Jordan

³Karak Teaching Hospital. Muta University

Cite this paper:
Professor Khitam Al-Refu, Heba Al-lala and Hiba Harbi. A Rare Clinical Manifestation of Piebaldism: Case Report and Review of Literature. American Journal of Medical Case Reports. 2025; 13(8):50-51. doi: 10.12691/ajmcr-13-8-2

Abstract

Piebaldism is a rare autosomal dominant genetic disorder characterized by congenitalareas of depigmentation in a specific pattern. The condition is commonly marked by a white depigmented patchon the scalp and forehead, observed in 80-90% of cases. Depigmentation can also extend to the eyebrows, eyelashes, and nasal root. In rare instances, hypopigmented or depigmented patches may extend to atypical sites such as the chin, anterior neck, trunk, abdomen, and limbs. This case report presents an unusual manifestation of Piebaldism, highlighting the variability of clinical manifestations associated with this genetic condition.

Keywords:
Piebaldism Depigmentation Pediatric

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