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Treadwell PA. Systemic conditions in children associated with pigmentary changes. Clin Dermatol. 2015 May-Jun; 33(3): 362-7.

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Article

A Rare Clinical Manifestation of Piebaldism: Case Report and Review of Literature

1Faculty of Medicine, Muta University

2School of Medicine, the University of Jordan, Amman 11418, Jordan

3Karak Teaching Hospital. Muta University


American Journal of Medical Case Reports. 2025, Vol. 13 No. 8, 50-51
DOI: 10.12691/ajmcr-13-8-2
Copyright © 2025 Science and Education Publishing

Cite this paper:
Professor Khitam Al-Refu, Heba Al-lala, Hiba Harbi. A Rare Clinical Manifestation of Piebaldism: Case Report and Review of Literature. American Journal of Medical Case Reports. 2025; 13(8):50-51. doi: 10.12691/ajmcr-13-8-2.

Correspondence to: Professor  Khitam Al-Refu, Faculty of Medicine, Muta University. Email: Alrefukhi@yahoo.com

Abstract

Piebaldism is a rare autosomal dominant genetic disorder characterized by congenitalareas of depigmentation in a specific pattern. The condition is commonly marked by a white depigmented patchon the scalp and forehead, observed in 80-90% of cases. Depigmentation can also extend to the eyebrows, eyelashes, and nasal root. In rare instances, hypopigmented or depigmented patches may extend to atypical sites such as the chin, anterior neck, trunk, abdomen, and limbs. This case report presents an unusual manifestation of Piebaldism, highlighting the variability of clinical manifestations associated with this genetic condition.

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