Multilocular Cystic Nephroma in a Child: A Rare Case

Mazaher Ramezani¹, Maryam Mirzaei¹, Mahya Alsadat Bagheri Mousavi² and Masoud Sadeghi^3,

¹Molecular Pathology Research Center, Emam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

²Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

³Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

Cite this paper:
Mazaher Ramezani, Maryam Mirzaei, Mahya Alsadat Bagheri Mousavi and Masoud Sadeghi. Multilocular Cystic Nephroma in a Child: A Rare Case. American Journal of Cancer Prevention. 2017; 5(2):25-27. doi: 10.12691/ajcp-5-2-2

Abstract

Multilocular cystic nephroma (MLCN) is classically described as a benign slow-growing renal tumor. The aim of this study was to evaluate MLCN in a child in the West of Iran. The ultrasound examination showed a multicystic mass measuring 6.6x6.5 cm with multiple internal septae in the middle and lower left kidney in a 19-month-old boy. Another sonography revealed multicystic mass 7.4x6.6cm in left renal pole with a diagnosis of multicystic nephroma. The lab data were within normal limits, except for hemoglobin level, that was 11.6 g/dl. The gross examination revealed kidney tissue measuring 10x8x7 cm including multiloculated cyst measuring up to 8 cm and the microscopic examination revealed multiple cysts lined by flat epithelium with spindle cell stroma containing abortive tubular elements and rare foci of small round cells. In conclusion, MLCN occures more in male children and female adults. The results showed that low hemoglobin level had association with some cases of MLCN. Inflammation may be seen in MLCN, but presence of any amount of blastemal cells is diagnosed as cystic partially differentiated nephroblastoma by most experts.

Keywords:
Multilocular cystic nephroma children case report

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