Pancreatic Ewings Sarcoma- A Dreadful Tumor

Kumar Jayant^1, , Swati Agrawal², Rajendra Agarwal³ and Susheela Khoiwal⁴

¹Department of Surgery, Sudha Hospital &Medical Research Centre, Talwandi, Kota, Rajasthan, India

²Sudha Hospital & Medical Research Centre Kota, Rajasthan, India

³Head of Dept of Surgery, Sudha Hospital &Medical Research Centre Kota, Rajasthan, India

⁴Department of Obs & Gynae, RNT Medical College, Udaipur

Cite this paper:
Kumar Jayant, Swati Agrawal, Rajendra Agarwal and Susheela Khoiwal. Pancreatic Ewings Sarcoma- A Dreadful Tumor. American Journal of Cancer Prevention. 2013; 1(3):24-26. doi: 10.12691/ajcp-1-3-2

Abstract

Extraosseous Ewing’s sarcoma/primitive neuroectodermal tumor (ES/PNET) is an uncommon, aggressive, and malignant tumor with poor outcome. Pancreas in one of the very rare extraosseous location for this tumor thus minimal information regarding this disorder is present in literature. The present case was clinically and radiologically misdiagnosed as a pancreatic tumor. Histopathology of the tumor tissue revealed “small round cells” that were positive for CD99 (MIC-2), confirming the diagnosis of ES/PNET. This case report emphasis on the importance of considering Ewing’s sarcoma in the differential diagnosis of intraabdominal, extraintestinal masses particularly in young patients presenting with pancreatic mass.

Keywords:
extraosseous ewing’s sarcoma pancreatic carcinoma atypical pancreatic carcinoma primitive neuroectodermal tumor

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References:

[1]	De Alava E, Gerald WL. Molecular biology of the Ewing sarcoma/primitive neuroectodermal tumor family. J ClinOncol 2000; 18:204-213.
[2]	Bulchmann G, Schuster T, Haas RJ et al. Primitive neuroectodermal tumor of the pancreas. An extremely rare tumor. Case report and review of the literature. KlinPadiatr 2000; 212: 185-188.
[3]	Danner DB, Hruban RH, Pitt HA et al. Primitive neuroectodermal tumor arising in the pancreas. Mod Pathol 1994; 7:200-204.
[4]	Perek S, Perek A, Sarman K et al. Primitive neuroectodermal tumor of the pancreas. A case report of an extremely rare tumor. Pancreatology 2003; 3:352-356.
[5]	Reilly C, Zenoni S, Hasan MK et al. Primary pancreatic Ewing's sarcoma with portal vein tumor thrombosis. J Gastrointest Surg. 2013 May; 17(5):1015-9.
[6]	Moschovi M, Trimis G, Stefanaki K et al. Favorable outcome of Ewing sarcoma family tumors to multiagent intensive preoperative chemotherapy: a single institution experience. J SurgOncol 2005; 89: 239-243.
[7]	Eralp Y, Bavbek S, Basaran M et al. Prognostic factors and survival in late adolescent and adult patients with small round cell tumors. Am J ClinOncol 2002; 25: 418-424.