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Sparrow A, Dambergs B, Bindon K, Smith P, Close D. Interaction of Grape Skin, Seed, and Pulp Tissues on Tannin and Anthocyanin Extraction in Pinot noir Wines. American Journal of Enology and Viticulture, 66.

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Effects of a Fermented Grape Combined with Specified Fruits and Vegetables or Their Extracts on Anti-aging and Anti-inflammatory Status: A Randomized Controlled Clinical Trial

1Institute of Food Safety and Risk Management, National Taiwan Ocean University, Keelung, Taiwan

2Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan;Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, Taiwan

3Shanghai Daerwei Biotechnology R&D Co., Ltd., Shanghai, China

4Department of Health and Beauty, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan

5Department of Cosmetic Science and Institute of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan, Taiwan

6Research & Design Center, TCI CO., Ltd., Taipei, Taiwan


Journal of Food and Nutrition Research. 2021, Vol. 9 No. 6, 292-296
DOI: 10.12691/jfnr-9-6-4
Copyright © 2021 Science and Education Publishing

Cite this paper:
Yung-Kai Lin, Yu-Yu Kao, Cheng Liu, Chia-Hua Liang, Yung-Hsiang Lin, Wei-Chun Hu, Chi-Fu Chiang. Effects of a Fermented Grape Combined with Specified Fruits and Vegetables or Their Extracts on Anti-aging and Anti-inflammatory Status: A Randomized Controlled Clinical Trial. Journal of Food and Nutrition Research. 2021; 9(6):292-296. doi: 10.12691/jfnr-9-6-4.

Correspondence to: Chi-Fu  Chiang, Research & Design Center, TCI CO., Ltd., Taipei, Taiwan. Email: Jimmy.Chiang@tci-bio.com

Abstract

Vegetables and fruits had antioxidant capacity. Fermented grapes had a higher content of anthocyanins and flavonoids, and reduced skin wrinkles. There were not more clinical studies on whether fermented grapes with fruit and vegetable extracts had anti-aging and anti-inflammatory activities. The current study used fermented grapes beverages made from fermented grapes combined with fruit and vegetable extracts to explore anti-aging and anti-inflammatory. 60 subjects were recruited and divided into a placebo and another fermented grape drinks group. The subjects drank 50 ml , 1 bottle a day for 8 week. After drinking for 8 weeks, a skin test and blood inflammatory factor analysis were performed. Compared to the placebo group, skin brightness, moisture, elasticity was significantly increased by 3.6%, 4.9%, 5.4%, respectively. Fermented grape drinks decreased skin spots, and wrinkles by 7.0%, and 19.0%, respectively. TNF-¦Á (Tumor Necrosis Factor) and IL-6 (Interleukin-6) expression were decreased, also, as a function of fermented grape drinks intakes. This study indicated that fermented grapes combined with fruit and vegetable extracts can significantly improve the brightness, moisture, elasticity, wrinkles, pores, and decrease TNF-¦Á and IL-6 expression.

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