BIOCHEMICAL APPROACH TO SEPSIS: A MINIREVIEW

Priyanka A^1, , Venkatesha ², Wilma Delphine Silvia CR³ and Venkata Bharat Kumar Pinnelli⁴

¹Department of Biochemistry, Bowring and Lady Curzon Medical College and Research Institute, Bangalore-560001

²Department of Biochemistry, Bowring and Lady Curzon Medical College and Research Institute, Bangalore-560002

³Department of Biochemistry, Bowring and Lady Curzon Medical College and Research Institute, Bangalore-560003

⁴Department of Biochemistry, Vydehi Institute of Medical Sciences and Research Centre, Bangalore-560066

Cite this paper:
Priyanka A, Venkatesha , Wilma Delphine Silvia CR and Venkata Bharat Kumar Pinnelli. BIOCHEMICAL APPROACH TO SEPSIS: A MINIREVIEW. International Journal of Clinical and Diagnostic Research. 2020; 8(5):91-103. doi: 10.12691/ijcdr-8-5-2

Abstract

Sepsis remains a major reason behind morbidity and mortality among all age groups. The ability to promptly and accurately diagnose sepsis with supported clinical evaluation and laboratory blood tests remain challenging. Recent advances in molecular technologies have increased investigations into the utility as diagnostic tools for sepsis. A systems-level understanding of sepsis, obtained by using new technologies may cause new diagnostic tools for sepsis. Despite the emerging need, future studies need to address the challenges of integrating with laboratory and clinical data so as to translate outcomes into precision medicine for sepsis. More research is required to validate the recent findings so as to integrate clinical and laboratory findings for future translation into precision medicine for sepsis. This mini review will discuss the possible applications and identification of recent biomarkers and diagnostic signatures for sepsis.

Keywords:
Sepsis Inflammatory Infection Biomarkers

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