American Journal of Medical Sciences and Medicine
ISSN (Print): 2327-6681 ISSN (Online): 2327-6657 Website: https://www.sciepub.com/journal/ajmsm Editor-in-chief: Apply for this position
Open Access
Journal Browser
Go
American Journal of Medical Sciences and Medicine. 2025, 13(2), 23-28
DOI: 10.12691/ajmsm-13-2-2
Open AccessArticle

Patterns of Upper Gastrointestinal Endoscopic Findings at Endoscopy Unit of Jimma University Medical Center, Jimma, Ethiopia

Beyan Mohammed Beshir1, Wasihun Zerfu Zewde2, Tsion Haile Woldemariam1, , Asfaw Hagos Shumye2, Dagim Kassahun Minasie2, Mohammed Kedir Shukri2 and Emebet Woldearegay Bereka3

1Arba Minch University College of Medicine and Health Sciences, Arba Minch, Ethiopia

2Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia

3Jimma University Medical Center, Jimma, Ethiopia

Pub. Date: July 13, 2025

Cite this paper:
Beyan Mohammed Beshir, Wasihun Zerfu Zewde, Tsion Haile Woldemariam, Asfaw Hagos Shumye, Dagim Kassahun Minasie, Mohammed Kedir Shukri and Emebet Woldearegay Bereka. Patterns of Upper Gastrointestinal Endoscopic Findings at Endoscopy Unit of Jimma University Medical Center, Jimma, Ethiopia. American Journal of Medical Sciences and Medicine. 2025; 13(2):23-28. doi: 10.12691/ajmsm-13-2-2

Abstract

Background: Upper gastrointestinal (GI) disorders are common causes of morbidity worldwide, presenting diagnostic and therapeutic challenges. Endoscopy remains the gold standard for diagnosing these conditions. However, data on the regional patterns of upper GI diseases in Ethiopia are limited. This study aimed to describe the endoscopic findings and their associations among patients undergoing upper GI endoscopy at Jimma University Medical Center (JUMC). Methods: A retrospective descriptive study reviewed endoscopy reports and medical records of 435 patients who underwent upper GI endoscopy at JUMC between September 2021 and September 2022. Data on sociodemographic characteristics, clinical indications, and endoscopic findings were analyzed using descriptive statistics, and associations between clinical features and diagnoses were examined. Results: The mean age of patients was approximately 42.5 (SD ± 16.8), with males constituting 52%. The most common indications for endoscopy were dyspepsia (30.11%), dysphagia (20.69%), and upper GI bleeding (18.39%). Erosive gastritis was the most frequent endoscopic finding, observed in 47.35% of cases, followed by duodenal ulcer (31.7%), GERD (17.9%), and esophageal cancer (14%). Notably, esophageal cancer accounted for 14% of findings, highlighting its significance in this population. Benign lesions predominated among patients under 45 years, whereas malignant lesions like esophageal cancer were more common in older age groups. There was a significant association between certain indications (e.g., dysphagia, bleeding) and specific diagnoses (p<0.05). Conclusion: The study underscores the predominance of benign inflammatory conditions, such as erosive gastritis, and highlights the considerable presence of esophageal cancer among patients undergoing endoscopy at JUMC. These findings suggest the need to improve endoscopic access, implement early detection programs, and develop targeted interventions to address the regional burden of upper GI diseases.

Keywords:
Endoscopy Upper Gastrointestinal Tract Epidemiology Diagnosis Ethiopia

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Fukudo, S. (2007). Pathophysiology of functional gastrointestinal disorders. Journal of Gastroenterology and Hepatology, 22(Suppl 1), S1–S5.
 
[2]  Vakil, N., van Zanten, S. V., Kahrilas, P., et al. (2017). Global consensus on the diagnosis and management of gastroesophageal reflux disease: GASS-CODE. Gastroenterology, 152(2), 431–445.
 
[3]  Moayyedi, P., & Talley, N. (2011). Healthcare burden and management of gastroesophageal reflux disease. Best Practice & Research Clinical Gastroenterology, 25(4), 505–516.
 
[4]  Eusebi, L. H., Ricciardiello, L., Corleto, V. D., et al. (2014). The epidemiology of gastric cancer. Gastroenterology Clinics of North America, 43(1), 13–26.
 
[5]  Global Burden of Disease Study 2017 Disease and Injury Incidence and Prevalence Collaborators. (2020). Global, regional, and national burden of gastrointestinal diseases. The Lancet Gastroenterology & Hepatology, 5(7), 721–772.
 
[6]  El-Serag, H. B. (2007). Epidemiology of gastroesophageal reflux disease. Gastroenterology Clinics of North America, 36(2), 261–276.
 
[7]  Okpokoro, B., O’Leary, C., & Kola, B. (2012). Upper gastrointestinal diseases in sub-Saharan Africa: A review. South African Journal of Epidemiology, 17(2), 48–52.
 
[8]  Teshale, A. B., & Tafese, G. (2017). Endoscopic findings among patients with dyspepsia in Ethiopia: A six-year review. Ethiopian Journal of Health Sciences, 27(4), 366–373.
 
[9]  Amarasena, N., & McColl, K. E. (2010). Helicobacter pylori infection and gastric diseases. Journal of Gastroenterology and Hepatology, 25(Suppl 2), S170–S174.
 
[10]  World Health Organization. (2014). Helicobacter pylori and gastric cancer [Fact sheet]. https://www.who.int/news-room/fact-sheets/detail/helicobacter-pylori-and-gastric-cancer.
 
[11]  Mayne, S., & Mayne, L. (2004). Regional variations in gastrointestinal disease patterns. World Journal of Gastroenterology, 10(10), 1404–1408.
 
[12]  Daba, L., Kassa, H., & Mamo, A. (2018). Endoscopic evaluation of Ethiopian patients: Spectrum of findings. Ethiopian Journal of Health Development, 32(2), 106–112.
 
[13]  Gebretsadik, D., et al. (2015). Retrospective study of upper GI endoscopic findings in Jimma University Medical Center, Ethiopia. Ethiopian Medical Journal, 53(2), 135–140. Retrieved from https://emjema.org.
 
[14]  Tessema, B., et al. (2013). Pattern of gastrointestinal endoscopic findings in Ethiopia: A review. Ethiopian Journal of Health Sciences, 23(2), 125–130. Retrieved from https:// www.ethjhealths.org.
 
[15]  Asrat, A., et al. (2017). Endoscopic findings in adult Ethiopian patients with dyspepsia. Ethiopian Journal of Health Development, 31(1), 36–41.
 
[16]  Mulu, A., et al. (2014). Prevalence of Helicobacter pylori infection among dyspeptic patients in Ethiopia. Ethiopian Medical Journal, 52(Suppl 1), S23–S30. Retrieved from https://emjema.org.
 
[17]  Wondwossen, A., et al. (2019). Distribution of gastric cancer in Ethiopia: A review. Ethiopian Journal of Health Sciences, 29(2), 147–154. Retrieved from https://www.ethjhealths.org.
 
[18]  Musa BM, et al. Upper gastrointestinal endoscopy findings in Sudanese patients: a cross-sectional study. Sudan J Med Sci. 2016; 11(3): 147-54.
 
[19]  Kamran M, Fawwad A, Haider SI, Hussain T. Upper gastrointestinal tract disorders: epidemiology, diagnosis, and management. Pak J Med Sci. 2021; 37 (1): 9-15.
 
[20]  Hassen SA, et al. Trends in upper gastrointestinal endoscopic findings in Ethiopia: a retrospective study. BMC Gastroenterol. 2019; 19: 157.
 
[21]  Gebreyesus HT, et al. Patterns of upper gastrointestinal diseases and endoscopic findings in Ethiopia: a 15-year review at Tikur Anbessa Hospital. Ethiop J Health Sci. 2021; 31(3): 345-52.
 
[22]  Kaggwa S, et al. Upper gastrointestinal endoscopy findings in southwestern Uganda: a prospective study. Afr Health Sci. 2020; 20(1): 123-30.
 
[23]  Kaye F, Ngom P. Environmental and lifestyle factors in East African esophageal cancer. Int J Cancer. 2014; 135(2): 255-61.
 
[24]  Cronin S, et al. Environmental carcinogens and esophageal cancer in East Africa. Environ Health Perspect. 2018; 126(8): 087002.
 
[25]  Dent J, El-Serag HB. Epidemiology of GERD: a global perspective. Gut. 2017; 66(7): 1302-10.
 
[26]  Kassa GM, et al. Late diagnosis and outcomes of gastrointestinal cancers in Ethiopia. Cancer Epidemiol. 2019; 60: 1-9.