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American Journal of Infectious Diseases and Microbiology
ISSN (Print): 2328-4056 ISSN (Online): 2328-4064 Website: https://www.sciepub.com/journal/ajidm Editor-in-chief: Maysaa El Sayed Zaki
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American Journal of Infectious Diseases and Microbiology. 2024, 12(1), 9-15
DOI: 10.12691/ajidm-12-1-2
Open AccessReview Article

Human Papilloma Virus: A Comprehensive Review

Shreya Veggalam1, Venkataramana Kandi2, and Srikar Reddy Vummenthala3

1Third Year MBBS Student at Prathima Institute of Medical Sciences

2Department of Microbiology Prathima Institute of Medical Sciences

3Final Year MBBS Student at Government Medical College Nalgonda

Pub. Date: January 15, 2024
View Full Text Full Text PDF (187 KB) Full Text ePUB(114 KB)

Cite this paper:
Shreya Veggalam, Venkataramana Kandi and Srikar Reddy Vummenthala. Human Papilloma Virus: A Comprehensive Review. American Journal of Infectious Diseases and Microbiology. 2024; 12(1):9-15. doi: 10.12691/ajidm-12-1-2

Abstract

Human Papillomavirus (HPV) is among several Deoxyribonucleic acid (DNA) viruses that can infect humans. HPV is a tumorigenic virus associated with carcinoma of the cervix in females. Additionally, HPV was found to be involved in the development of oropharyngeal and anogenital cancers. Cervical cancer is the second most predominant cancer resulting in death among women worldwide. Despite the availability of an approved vaccine, there is little awareness about the vaccine that could be administered to prevent HPV-associated cancers. HPV has been causing trouble in the lives of millions of women globally. The majority of HPV-associated cancers remain unrecognized due to the lack of specific symptoms. Additionally, women who are infected at an early age develop symptoms after decades, thereby complicating the treatment and contributing to the worsening of disease outcomes. HPV appears in several hundreds of serotypes with some of them being primarily responsible for most of the disease-causing complications including cancer. It is high time for the Indian government and other administrations, especially those belonging to developing and underdeveloped countries, throughout the world to consider the implementation of the HPV vaccination. Besides, it is extremely important to enforce preventive screening of women for cervical cancer at regular intervals since early diagnosis enables initiation of treatment and minimizes morbidity and mortality. In this review, we comprehensively discuss the epidemiology, pathogenicity, complications, diagnosis, management, and prevention of HPV-associated diseases including cancer.

Keywords:
Human Papillomavirus (HPV) cervical cancer women vaccination preventive screening cancer carcinoma HPV vaccination epidemiology pathogenesis

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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