Separation of the Enantiomers of Lactide, Lactic Acid Dimer, for a Sustainable Bioplastic Management

Nathalie Berezina^1, , Nicolas Landercy¹, Pierre-Antoine Mariage^{2, 3} and Benoit Morea²

¹Green Chemistry Department, Materia Nova R&D Center, Ghislenghien, Belgium

²R&D Department, Galactic SA, Escanaffles, Belgium

³R&D Department, Green2Chem, Leuze, Belgium

Cite this paper:
Nathalie Berezina, Nicolas Landercy, Pierre-Antoine Mariage and Benoit Morea. Separation of the Enantiomers of Lactide, Lactic Acid Dimer, for a Sustainable Bioplastic Management. World Journal of Organic Chemistry. 2013; 1(2):20-23. doi: 10.12691/wjoc-1-2-3

Abstract

Despite the small difference in the steric hindrance of the substitutes of the asymmetric carbon of the lactic acid, a way for the desymmetrization of the racemic mixture was discovered. Two possibilities have arisen: the synthesis and further separation of diastereoisomers with the (S)-2-methyl-1-butanol as chiral auxiliary and the kinetic discrimination during the esterification with the (R)-(-)-Myrtenol.

Keywords:
lactide enantiomeric separation diastereoisomers PLA bioplastics

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