[1] | Keys A, A.C., Van Buchem FSP The diet and all-causes death rate in the Seven Countries Study. Lancet, 1981. 2(8237): p. 58-61. |
|
[2] | Boring, C.C., T.S. Squires, and T. Tong, Cancer statistics, 1992. CA Cancer J Clin, 1992. 42(1): p. 19-38. |
|
[3] | Minotti, G., et al., Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev, 2004. 56(2): p. 185-229. |
|
[4] | Owen, R.W., et al., Olive-oil consumption and health: the possible role of antioxidants. Lancet Oncol, 2000. 1: p. 107-12. |
|
[5] | Tripoli, E., et al., The phenolic compounds of olive oil: structure, biological activity and beneficial effects on human health. Nutr Res Rev, 2005. 18(1): p. 98-112. |
|
[6] | Goldsmith, C.D., et al., Phytochemical properties and anti-proliferative activity of Olea europaea L. leaf extracts against pancreatic cancer cells. Molecules, 2015. 20(7): p. 12992-3004. |
|
[7] | Fayyaz, S., et al., Oleuropein mediated targeting of signaling network in cancer. Curr Top Med Chem, 2016. 16. |
|
[8] | Andreadou, I., et al., The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic effects in anesthetized rabbits. J Nutr, 2006. 136(8): p. 2213-9. |
|
[9] | Andreadou, I., et al., Acute doxorubicin cardiotoxicity is successfully treated with the phytochemical oleuropein through suppression of oxidative and nitrosative stress. J Mol Cell Cardiol, 2007. 42(3): p. 549-58. |
|
[10] | DiPaola, R.S., et al., Therapeutic starvation and autophagy in prostate cancer: a new paradigm for targeting metabolism in cancer therapy. Prostate, 2008. 68(16): p. 1743-52. |
|
[11] | Mathew, R., V. Karantza-Wadsworth, and E. White, Role of autophagy in cancer. Nat Rev Cancer, 2007. 7(12): p. 961-7. |
|
[12] | Shintani, T. and D.J. Klionsky, Autophagy in health and disease: a double-edged sword. Science, 2004. 306(5698): p. 990-5. |
|
[13] | Kabeya, Y., et al., LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J, 2000. 19(21): p. 5720-8. |
|
[14] | Zoidou, E., et al., Identification of Throuba Thassos, a traditional Greek table olive variety, as a nutritional rich source of oleuropein. J Agric Food Chem, 2010. 58(1): p. 46-50. |
|
[15] | Kaighn, M.E., et al., Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest Urol, 1979. 17(1): p. 16-23. |
|
[16] | Vistica, D.T., et al., Tetrazolium-based assays for cellular viability: a critical examination of selected parameters affecting formazan production. Cancer Res, 1991. 51(10): p. 2515-20. |
|
[17] | Le Belle, J.E., et al., A comparison of cell and tissue extraction techniques using high-resolution 1H-NMR spectroscopy. NMR Biomed, 2002. 15(1): p. 37-44. |
|
[18] | Pechlivanis, A., et al., (1)H NMR-based metabonomic investigation of the effect of two different exercise sessions on the metabolic fingerprint of human urine. J Proteome Res, 2010. 9(12): p. 6405-16. |
|
[19] | Tenta, R., et al., Bone microenvironment-related growth factors modulate differentially the anticancer actions of zoledronic acid and doxorubicin on PC-3 prostate cancer cells. Prostate, 2004. 59(2): p. 120-31. |
|
[20] | Kapadia, G.J., et al., Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines. J Complement Integr Med, 2013. 10: p. 113-122. |
|
[21] | Das, A., et al., Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. Proc Natl Acad Sci U S A, 2010. 107(42): p. 18202-7. |
|
[22] | Katsoulieris, E.N., The olive leaf extract oleuropein exerts protective effects against oxidant-induced cell death, concurrently displaying pro-oxidant activity in human hepatocarcinoma cells. Redox Rep, 2016. 21(2): p. 90-7. |
|
[23] | Giner, E., et al., Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice. Mol Nutr Food Res, 2016. 60(2): p. 242-55. |
|
[24] | Cheng, J.S., et al., The effect of oleuropein from olive leaf (Olea europaea) extract on Ca(2+) homeostasis, cytotoxicity, cell cycle distribution and ROS signaling in HepG2 human hepatoma cells. Food Chem Toxicol, 2016. 91: p. 151-66. |
|
[25] | Acquaviva, R., et al., Antiproliferative effect of oleuropein in prostate cell lines. Int J Oncol, 2012. 41(1): p. 31-8. |
|
[26] | Hippert, M.M., P.S. O'Toole, and A. Thorburn, Autophagy in cancer: good, bad, or both? Cancer Res, 2006. 66(19): p. 9349-51. |
|
[27] | Singletary, K. and J. Milner, Diet, autophagy, and cancer: a review. Cancer Epidemiol Biomarkers Prev, 2008. 17(7): p. 1596-610. |
|
[28] | Kaur, J. and J. Debnath, Autophagy at the crossroads of catabolism and anabolism. Nat Rev Mol Cell Biol, 2015. 16(8): p. 461-72. |
|
[29] | Ortega, A.L., S. Mena, and J.M. Estrela, Glutathione in cancer cell death. Cancers (Basel), 2011. 3(1): p. 1285-310. |
|
[30] | Jorgenson, T.C., W. Zhong, and T.D. Oberley, Redox imbalance and biochemical changes in cancer. Cancer Res, 2013. 73(20): p. 6118-23. |
|
[31] | Kawaguchi, M., et al., Autophagy is an important metabolic pathway to determine leukemia cell survival following suppression of the glycolytic pathway. Biochem Biophys Res Commun, 2016. 474(1): p. 188-92. |
|
[32] | Lilienbaum, A., Relationship between the proteasomal system and autophagy. Int J Biochem Mol Biol, 2013. 4(1): p. 1-26. |
|
[33] | Ding, W.X., et al., Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol, 2007. 171(2): p. 513-24. |
|
[34] | Copeland, R.J., J.W. Bullen, and G.W. Hart, Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity. Am J Physiol Endocrinol Metab, 2008. 295(1): p. E17-28. |
|
[35] | de Queiroz, R.M., E. Carvalho, and W.B. Dias, O-GlcNAcylation: The Sweet Side of the Cancer. Front Oncol, 2014. 4: p. 132. |
|
[36] | Munkley, J., I.G. Mills, and D.J. Elliott, The role of glycans in the development and progression of prostate cancer. Nat Rev Urol, 2016. 13(6): p. 324-33. |
|
[37] | Itkonen, H.M., et al., O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells. Cancer Res, 2013. 73(16): p. 5277-87. |
|
[38] | Leri, M., et al., The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies. J Nutr Biochem, 2016. 30: p. 153-66. |
|
[39] | Potocnjak, I., et al., Oral administration of oleuropein attenuates cisplatin-induced acute renal injury in mice through inhibition of ERK signaling. Mol Nutr Food Res, 2016. 60(3): p. 530-41. |
|