The Correlation between Peri-implant Bone Density and the Biological Implant Stability: A Two Years Follow-up

Walid S. Salem^{1, 2}, Mohamed R. Mahmoud³, Wael M. Zakaria^3, and Yasser A. Araby³

¹Department Oral and Maxillofacial Radiology, Beni Suef University, Egypt

²Department Oral and Maxillofacial Surgery and Diagnostic Science, Prince Sattam bin Abdul Aziz University, Saudi Arabia

³Department of Prosthetic Dental Sciences, College of Dentistry, Qassim University, Saudi Arabia

Cite this paper:
Walid S. Salem, Mohamed R. Mahmoud, Wael M. Zakaria and Yasser A. Araby. The Correlation between Peri-implant Bone Density and the Biological Implant Stability: A Two Years Follow-up. International Journal of Dental Sciences and Research. 2018; 6(2):48-52. doi: 10.12691/ijdsr-6-2-6

Abstract

Objective: The aim of this study was to assess the correlation between the peri-implant bone density and the biological stability around dental implants. Materials and Methods: A total of 56 implants were placed in the mandibular canine area of 28 patients to retain mandibular overdentures. The assessment of bone density changes was obtained through Cone-Beam Computed Tomography (CBCT) and the assessment of implant stability was obtained through Resonance Frequency Analysis (RFA) at loading time, and after 6, 12, 24 months. Results: RFA measurement showed a mean of 67.5± 5.8 ISQ at loading time and a mean of 71.3±5.5 ISQ after 24 months. Bone density around the implants showed a mean of 683.48±78.63 HU at loading time, and a mean of 722.24±58.4 HU after 24 months. These increases were statistically significant (p˂0.05). Conclusion: The biological implant stability as measured using the Resonance Frequency Analysis (RFA) and the peri-implant bone density as measured using Cone Beam Computed Tomography (CBCT) showed a significant moderate positive correlation.

Keywords:
biological stability bone density resonance frequency analysis cone beam computed tomography

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References:

[1]	Le Guehennec L, Soueidan A, Layrolle P, Amouriq Y. Surface treatments of titanium dental implants for rapid osseointegration. Dental materials: official publication of the Academy of Dental Materials. 2007; 23(7): 844-54.
[2]	Molly L. Bone density and primary stability in implant therapy. Clinical oral implants research. 2006; 17 Suppl 2: 124-35.
[3]	Esposito M, Hirsch JM, Lekholm U, Thomsen P. Biological factors contributing to failures of osseointegrated oral implants. (II). Etiopathogenesis. European journal of oral sciences. 1998; 106(3): 721-64.
[4]	Felsenberg D, Boonen S. The bone quality framework: determinants of bone strength and their interrelationships, and implications for osteoporosis management. Clinical therapeutics. 2005; 27(1): 1-11.
[5]	Bouxsein ML. Bone quality: where do we go from here? Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2003;14 Suppl 5: S118-27.
[6]	Friberg B, Sennerby L, Linden B, Grondahl K, Lekholm U. Stability measurements of one-stage Branemark implants during healing in mandibles. A clinical resonance frequency analysis study. International journal of oral and maxillofacial surgery. 1999; 28(4): 266-72.
[7]	van Steenberghe D, Quirynen M, Molly L, Jacobs R. Impact of systemic diseases and medication on osseointegration. Periodontology 2000. 2003; 33: 163-71.
[8]	Sennerby L, Roos J. Surgical determinants of clinical success of osseointegrated oral implants: a review of the literature. The International journal of prosthodontics. 1998; 11(5): 408-20.
[9]	Atsumi M, Park SH, Wang HL. Methods used to assess implant stability: current status. The International journal of oral & maxillofacial implants. 2007; 22(5): 743-54.
[10]	Zhou W, Han C, Yunming L, Li D, Song Y, Zhao Y. Is the osseointegration of immediately and delayed loaded implants the same?--comparison of the implant stability during a 3-month healing period in a prospective study. Clinical oral implants research. 2009; 20(12): 1360-6.
[11]	Simunek A, Kopecka D, Brazda T, Strnad I, Capek L, Slezak R. Development of implant stability during early healing of immediately loaded implants. The International journal of oral & maxillofacial implants. 2012; 27(3): 619-27.
[12]	Lai HC, Zhang ZY, Wang F, Zhuang LF, Liu X. Resonance frequency analysis of stability on ITI implants with osteotome sinus floor elevation technique without grafting: a 5-month prospective study. Clinical oral implants research. 2008; 19(5): 469-75.
[13]	Geckili O, Bilhan H, Bilgin T. A 24-week prospective study comparing the stability of titanium dioxide grit-blasted dental implants with and without fluoride treatment. The International journal of oral & maxillofacial implants. 2009; 24(4): 684-8.
[14]	Barone A, Ricci M, Calvo-Guirado JL, Covani U. Bone remodelling after regenerative procedures around implants placed in fresh extraction sockets: an experimental study in Beagle dogs. Clinical oral implants research. 2011; 22(10): 1131-7.
[15]	Mano T, Ishikawa K, Harada K, Umeda H, Ueyama Y. Comparison of apatite-coated titanium prepared by blast coating and flame spray methods--evaluation using simulated body fluid and initial histological study. Dental materials journal. 2011; 30(4): 431-7.
[16]	Hasan I, Dominiak M, Blaszczyszyn A, Bourauel C, Gedrange T, Heinemann F. Radiographic evaluation of bone density around immediately loaded implants. Annals of anatomy = Anatomischer Anzeiger: official organ of the Anatomische Gesellschaft. 2015; 199: 52-7.
[17]	Barone A, Covani U, Cornelini R, Gherlone E. Radiographic bone density around immediately loaded oral implants. Clinical oral implants research. 2003; 14(5): 610-5.
[18]	Meredith N. Assessment of implant stability as a prognostic determinant. The International journal of prosthodontics. 1998; 11(5): 491-501.
[19]	Meredith N, Alleyne D, Cawley P. Quantitative determination of the stability of the implant-tissue interface using resonance frequency analysis. Clinical oral implants research. 1996; 7(3): 261-7.
[20]	Sennerby L, Meredith N. Implant stability measurements using resonance frequency analysis: biological and biomechanical aspects and clinical implications. Periodontology 2000. 2008; 47: 51-66.
[21]	Glauser R, Sennerby L, Meredith N, Ree A, Lundgren A, Gottlow J, et al. Resonance frequency analysis of implants subjected to immediate or early functional occlusal loading. Successful vs. failing implants. Clinical oral implants research. 2004; 15(4): 428-34.
[22]	Misch CE, Perel ML, Wang HL, Sammartino G, Galindo-Moreno P, Trisi P, et al. Implant success, survival, and failure: the International Congress of Oral Implantologists (ICOI) Pisa Consensus Conference. Implant dentistry. 2008; 17(1): 5-15.
[23]	Vercruyssen M, Jacobs R, Van Assche N, van Steenberghe D. The use of CT scan based planning for oral rehabilitation by means of implants and its transfer to the surgical field: a critical review on accuracy. Journal of oral rehabilitation. 2008; 35(6): 454-74.
[24]	Turkyilmaz I, Tozum TF, Tumer C, Ozbek EN. Assessment of correlation between computerized tomography values of the bone, and maximum torque and resonance frequency values at dental implant placement. Journal of oral rehabilitation. 2006; 33(12): 881-8.
[25]	Song YD, Jun SH, Kwon JJ. Correlation between bone quality evaluated by cone-beam computerized tomography and implant primary stability. The International journal of oral & maxillofacial implants. 2009; 24(1): 59-64.
[26]	Alsaadi G, Quirynen M, Michiels K, Jacobs R, van Steenberghe D. A biomechanical assessment of the relation between the oral implant stability at insertion and subjective bone quality assessment. Journal of clinical periodontology. 2007; 34(4): 359-66.
[27]	Snauwaert K, Duyck J, van Steenberghe D, Quirynen M, Naert I. Time dependent failure rate and marginal bone loss of implant supported prostheses: a 15-year follow-up study. Clinical oral investigations. 2000; 4(1): 13-20.
[28]	Miracle AC, Mukherji SK. Conebeam CT of the head and neck, part 1: physical principles. AJNR American journal of neuroradiology. 2009; 30(6): 1088-95.
[29]	Naitoh M, Aimiya H, Hirukawa A, Ariji E. Morphometric analysis of mandibular trabecular bone using cone beam computed tomography: an in vitro study. The International journal of oral & maxillofacial implants. 2010; 25(6): 1093-8.
[30]	Isoda K, Ayukawa Y, Tsukiyama Y, Sogo M, Matsushita Y, Koyano K. Relationship between the bone density estimated by cone-beam computed tomography and the primary stability of dental implants. Clinical oral implants research. 2012; 23(7): 832-6.
[31]	Misch CE, Wang HL, Misch CM, Sharawy M, Lemons J, Judy KW. Rationale for the application of immediate load in implant dentistry: Part I. Implant dentistry. 2004; 13(3): 207-17.
[32]	Salvi GE, Lang NP. Diagnostic parameters for monitoring peri-implant conditions. The International journal of oral & maxillofacial implants. 2004; 19 Suppl: 116-27.
[33]	Ito Y, Sato D, Yoneda S, Ito D, Kondo H, Kasugai S. Relevance of resonance frequency analysis to evaluate dental implant stability: simulation and histomorphometrical animal experiments. Clinical oral implants research. 2008; 19(1): 9-14.
[34]	da Cunha HA, Francischone CE, Filho HN, de Oliveira RC. A comparison between cutting torque and resonance frequency in the assessment of primary stability and final torque capacity of standard and TiUnite single-tooth implants under immediate loading. The International journal of oral & maxillofacial implants. 2004; 19(4): 578-85
[35]	Becker W, Sennerby L, Bedrossian E, Becker BE, Lucchini JP. Implant stability measurements for implants placed at the time of extraction: a cohort, prospective clinical trial. Journal of periodontology. 2005; 76(3): 391-7.
[36]	Sjostrom M, Lundgren S, Nilson H, Sennerby L. Monitoring of implant stability in grafted bone using resonance frequency analysis. A clinical study from implant placement to 6 months of loading. International journal of oral and maxillofacial surgery. 2005; 34(1): 45-51.
[37]	Barros RR, Novaes AB, Jr., Papalexiou V, Souza SL, Taba M, Jr., Palioto DB, et al. Effect of biofunctionalized implant surface on osseointegration: a histomorphometric study in dogs. Brazilian dental journal. 2009; 20(2): 91-8.
[38]	Aranyarachkul P, Caruso J, Gantes B, Schulz E, Riggs M, Dus I, et al. Bone density assessments of dental implant sites: 2. Quantitative cone-beam computerized tomography. The International journal of oral & maxillofacial implants. 2005; 20(3): 416-24.
[39]	Parsa A, Ibrahim N, Hassan B, van der Stelt P, Wismeijer D. Bone quality evaluation at dental implant site using multislice CT, micro-CT, and cone beam CT. Clinical oral implants research. 2015; 26(1): e1-7.
[40]	Ersanli S, Karabuda C, Beck F, Leblebicioglu B. Resonance frequency analysis of one-stage dental implant stability during the osseointegration period. Journal of periodontology. 2005; 76(7): 1066-71.
[41]	Gotfredsen K, Berglundh T, Lindhe J. Bone reactions adjacent to titanium implants with different surface characteristics subjected to static load. A study in the dog (II). Clinical oral implants research. 2001; 12(3): 196-201.
[42]	Salimov F, Tatli U, Kurkcu M, Akoglan M, Oztunc H, Kurtoglu C. Evaluation of relationship between preoperative bone density values derived from cone beam computed tomography and implant stability parameters: a clinical study. Clinical oral implants research. 2014; 25(9): 1016-21.
[43]	Tatli U, Salimov F, Kurkcu M, Akoglan M, Kurtoglu C. Does cone beam computed tomography-derived bone density give predictable data about stability changes of immediately loaded implants?: A 1-year resonance frequency follow-up study. The Journal of craniofacial surgery. 2014; 25(3): e293-9.
[44]	Huang H, Wismeijer D, Shao X, Wu G. Mathematical evaluation of the influence of multiple factors on implant stability quotient values in clinical practice: a retrospective study. Therapeutics and clinical risk management. 2016; 12: 1525-32.