Efficacy of NSAID (Lornoxicam) After Impacted Third-Molar Surgery With/Without Conscious Sedation: A Double-Blind Randomized Clinical Study

Ozkan Ozgul^1, and Selahattin Or²

¹Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kirikkale University, Kirikkale, Turkey

²Department of Oral and maxillofacial Surgery, Faculty of Dentistry, Ankara University, Ankara, Turkey

Cite this paper:
Ozkan Ozgul and Selahattin Or. Efficacy of NSAID (Lornoxicam) After Impacted Third-Molar Surgery With/Without Conscious Sedation: A Double-Blind Randomized Clinical Study. International Journal of Dental Sciences and Research. 2018; 6(1):1-5. doi: 10.12691/ijdsr-6-1-1

Abstract

Aim: Pain and swelling following surgery for impacted third molars can be controlled by various methods. This study compared the analgesic and anti-inflammatory efficacy and tolerability of lornoxicam, aspirin and a placebo with and without conscious sedation in impacted mandibular third-molar surgery. Materials and Methods: 60 patients undergoing third-molar surgery were divided into 2 groups of conscious sedation and routine local anesthesia (n=30). Both groups were divided into three subgroups (n=10) that received either Lornoxicam, aspirin, or a placebo postoperatively. Results: In both the conscious sedation and local anesthesia groups, swelling reduction was significantly greater with Lornoxicam compared to aspirin and placebo (p< .05). Pain values were significantly lower for Lornoxicam group compared to both aspirin and placebo groups at 6, 12 and 24 hours postoperatively (p< .05). Conclusion: Conscious sedation resulted less pain and swelling. Moreover, Lornoxicam was found to be an effective analgesic and anti-inflammatory agent for use in conjunction with oral surgery.

Keywords:
conscious sedation third molar surgery NSAID swelling pain clinical research

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