Efficacy of Ozone as an Adjunctive Anti-microbial in the Non-surgical Treatment of Chronic and Aggressive Periodontitis: A Systematic Review Protocol

Oluwatosin Tokede^1, , Yuri Jadotte² and Rufus Caine³

¹Dental Public Health, School of Public Health, Rutgers University

²Quantitative Methods, Epidemiology and Biostatistics, School of Public Health and School of Nursing, Rutgers University

³Dental Public Health, School of Public Health and Department of Oral Pathology and Diagnostic Services, School of Dental Medicine, Rutgers University

Cite this paper:
Oluwatosin Tokede, Yuri Jadotte and Rufus Caine. Efficacy of Ozone as an Adjunctive Anti-microbial in the Non-surgical Treatment of Chronic and Aggressive Periodontitis: A Systematic Review Protocol. International Journal of Dental Sciences and Research. 2016; 4(2):24-27. doi: 10.12691/ijdsr-4-2-3

Abstract

This is a protocol for a review so there is no abstract. The main objective of this review is to compute a summary effect for the adjunctive use of ozone with scaling and root planning (SRP) in the treatment of these diseases. This review will also seek to explore possible heterogeneity that may be present due to different ozone forms used during treatment.

Keywords:
periodontal diseases ozone therapy scaling and root planning clinical attachment level probing pocket depth plaque index bleeding on probing gingival index adjunct aggressive periodontitis chronic periodontitis

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]	Eke PI, Dye B, Wei L, Thornton-Evans G, Genco R (2012). Prevalence of Periodontitis in Adults in the United States: 2009 and 2010. J Dent Res: 1-7.
[2]	1999 International Workshop for a Classification of Periodontal Diseases and Conditions.
[3]	Joshipura V, Yadalam U, Brahmavar B. (2015). Aggressive periodontitis: A review. J Int Clin Dent Res Organ 7(1) :11-17.
[4]	Armitage GC (2000). Comparison of the microbiological features of chronic and aggressive periodontitis. Periodontol; 53: 70-88.
[5]	Schenkein HA (2006). Host responses in maintaining periodontal health and determining periodontal disease. Periodontol 2000; 40: 77-93 2006.
[6]	Otomo-Corgel J, Pucher JJ, Rethman MP, Reynolds MA. (2012). State of the Science: Chronic periodontitis and systemic health. J Evid Base Dent Pract, 12(3): 20-28.
[7]	Skurska A, Pietruska MD, Paniczko-Drężek A, Dolińska E, Zelazowska-Rutkowska B, Zak J, Pietruski J, Milewski R, Wysocka J (2010). Evaluation of the influence of ozonotherapy on the clinical parameters and MMP levels in patients with chronic and aggressive periodontitis. Adv Med Sci; 55(2):297-307.
[8]	Srikanth, A., Sathish, M., & Sri Harsha, A. V. (2013). Application of ozone in the treatment of periodontal disease. Journal of Pharmacy & Bioallied Sciences; 5(Suppl 1), S89-S94.
[9]	Tatsuya F, Kazuya M, Yoshimasa M , Shin-ichi F, Gotaro S, Yasuhiro I, Akihiko S, Pao-Li W (2014). Antimicrobial Effects of Ozone Gel Against Periodontal Bacteria. Journal of Hard Tissue Biology; 23(4) 445-448.
[10]	Gupta G, Mansi B (2012). Ozone therapy in periodontics. Journal of Medicine and Life; 5(1): 59‐67.
[11]	Saini, R. (2011) Ozone therapy in dentistry: A strategic review. Journal of Natural Science, Biology, and Medicine; 2(2), 151–153.
[12]	Maiya A (2011). Application of ozone in dentistry. Int J Clin Dent Sci; 2: 23-7.
[13]	Hayakumo, S., Arakawa, S., Mano, Y. and Izumi, Y (2013). Clinical and microbiological effects of ozone nanobubble water irrigation as an adjunct to mechanical subgingival debridement in periodontitis patients in a randomized controlled trial. Clinical Oral Investigations; 17: 379-388.
[14]	Huth KC, Jakob FM, Saugel B, Cappello C, Paschos E, Hollweck R, Hickel R, Brand K (2006). Effect of ozone on oral cells compared with established antimicrobials. Eur J Oral Sci; 114: 435-440.
[15]	Yilmaz S, Algan S, Gursoy H, Noyan U, Kuru B. E, Kadir, T (2013). Evaluation of the clinical and antimicrobial effects of the Er:YAG laser or topical gaseous ozone as adjuncts to initial periodontal therapy. Photomed Laser Surg; 31(6): 293-298 2013.
[16]	Ramfjord SP (1967). The periodontal disease index (PDI). J Periodontol; 6: 602-610.
[17]	Silness J, Loe H (1964). Periodontal disease in pregnancy 2. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand; 22: 121-135.
[18]	Loe H, Silness J (1963). Periodontal disease in pregnancy. Prevalence and severity. Acta Odontol Scand; 21:533-51.
[19]	Ainamo J, Bay I (1975). Problems and proposals for recording gingivitis and plaque. Int Dent J; 4: 229-35.
[20]	Higgins JPT, Green S (2011). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. Available from www.cochrane-handbook.org.
[21]	Whitehead A (2003). Meta-analysis of Controlled Trials. Published by John Wiley& Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex PO19 8SQ, England.