Bullous Pemphigoid A Rare Autoimmune Disease: A Case Report

Sharma Manek^1, , SP Saravanan¹ and Rai Rahul¹

¹Department of Periodontology, Army Dental Centre, New Delhi, India

Cite this paper:
Sharma Manek, SP Saravanan and Rai Rahul. Bullous Pemphigoid A Rare Autoimmune Disease: A Case Report. International Journal of Dental Sciences and Research. 2022; 10(1):1-3. doi: 10.12691/ijdsr-10-1-1

Abstract

Bullous pemphigoid [BP] is an autoimmune disorder characterized by the formation of autoantibodies causing blister formation potentially triggered by trauma, antimicrobials and non-steroidal anti-inflammatory drugs. A 31yearold female patient reported with complaint of fluid filled blisters which appear intermittently for past 2 years, leaving painful ulcerations. Incisional biopsy was performed, along with adjunctive use of Low Level Laser Therapy, report of which showed bullous pemphigoid and better healing due to LLLT respectively. Thus, based on our clinical experience and result the use of laser as an adjunctive therapy in symptomatic management of desquamative lesions is indeed a food for thought.

Keywords:
auto immune bullous pemphigoid low level laser therapy

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References:

[1]	Fuertes de Vega I., Iranzo-Fernández P, Mascaró-Galy JM, Penfigoideampolloso: guía de manejo práctico. Actas Dermosifiliogr. 105: 328-46.2014.
[2]	Lloyd-Lavery, A., Chi C.C., Wojnarowska F., Taghipour K. The associations between Bullous Pemphigoid and Drug use, JAMA Dermatology, 149(1), 58. 2013.
[3]	Bastuji-Garin S., Joly P., Lemordant P., Sparsa A., Bedane C., Richard M.A., Risk Factors for Bullous Pemphigoid in the Elderly: A Prospective Case–Control Study, J Invest Dermatol, 131(3), 637-43. 2011.
[4]	Hussain M.H., Tanweer F., Sakagiannis G., Mair M., Mahmood S., Ashok kumar S., Pemphigus Vulgaris and Bullous Pemphigoid of the Upper Aerodigestive Tract: A Review Article and Novel Approaches to Management, ORL, 1-9. 2021.
[5]	Yousef M, Mansouri P, Partovikia M, Esmaili M, Younespour S, Hassani L, The Effect of Low Level Laser Therapy on Pemphigus Vulgaris Lesions: A Pilot Study, J Lasers Med Sci, 8(4): 177-80. 2017.
[6]	Ujiie H., Nishie W., Shimizu H., Pathogenesis of bullous pemphigoid, Dermatol Clin, 29: 439-46.2011.
[7]	Schmidt E., Zillikens D., Pemphigoid diseases, Lancet, 381: 320-32.2013.
[8]	Taquin H., Chiaverini C., Lacour J.P., Spectrum of Clinical Responses to Therapies in infantile bullous pemphigoid, Pediatr Dermatol, 33: 77-81. 2016.
[9]	Erugula S.R., Singaraju D.K., Govada J, Rajajee K.T.S.S, Sudheer M.V.S, Kumar A.S., Bandaru B.K., Kumar K.M., Vesiculobullous lesions of the oral cavity, Int Arch Integr Med, 3(11): 154-163. 2016.
[10]	Rosenbach M.A., Karolyn W.A. Wanat, Lynm C., Bullous pemphigoid, JAMA Dermatol, 149: 3. 2013.
[11]	Lamberts A., Meijer J.M., Jonkman M.F., Nonbullous pemphigoid: A systematic review, J Am Acad Dermatol, 78: 989-95. 2018.
[12]	Anstey A., VenningV., Wojnarowska F., Bhogai B., Black M.M., Determination of the optimum site for diagnostic biopsy for direct immunofluorescence in bullous pemphigoid, Clin Exp Dermatol, 15(6), 438-441.1990.
[13]	Aparna P.V., Kailasam S., Namachivayam N., Gopinath J., Oral bullous pemphigoid – A rarity among vesiculobullous lesions. J Indian Acad Oral Med Radiol, 30: 4325. 2018.
[14]	Lee C.M., Lead better H.K., Fishman J.M., A case of oropharyngeal bullous pemphigoid presenting with haemoptysis, Case Rep in Otolaryngol, 1-4. 2015.