International Journal of Dental Sciences and Research
ISSN (Print): 2333-1135 ISSN (Online): 2333-1259 Website: https://www.sciepub.com/journal/ijdsr Editor-in-chief: Marcos Roberto Tovani Palone
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International Journal of Dental Sciences and Research. 2014, 2(1), 16-18
DOI: 10.12691/ijdsr-2-1-5
Open AccessReview Article

The Role of Antibiotics in Treatment of Chronic Periodontitis

Priyavadhana Prabhu1, , M.N. Prabhu2 and M. Elumalai3

1Research Scholar in Medical Microbiology, Bharath University, Chennai, India

2Department of Periodontics, Penang International Dental College, Penang, Malaysia

3Department of Pharmacology, Sree Balaji Dental College, Chennai, India

Pub. Date: January 20, 2014

Cite this paper:
Priyavadhana Prabhu, M.N. Prabhu and M. Elumalai. The Role of Antibiotics in Treatment of Chronic Periodontitis. International Journal of Dental Sciences and Research. 2014; 2(1):16-18. doi: 10.12691/ijdsr-2-1-5

Abstract

Systemic antibiotics may be a necessary adjunct in controlling bacterial infection because bacteria can invade periodontal tissues, making mechanical therapy alone sometimes ineffective. An ideal antibiotic for use in prevention and treatment of periodontal diseases should be specific for periodontal pathogens, allogenic and nontoxic, substantive, not in general use for treatment of other diseases, and inexpensive . Combination of antibiotics may be necessary to eliminate all putative pathogens from some periodontal pockets. The guidelines for use, structure and origin, mechanisms of action of antibiotics are discussed in this paper. Also the recommended antibiotic dosages in Periodontal therapy is reviewed in this paper.

Keywords:
plaque virulence micro organisms antimicrobials bacteria

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References:

[1]  A. J. van Winkelhoff, J. de Graaff, Microbiology in the management of destructive periodontal diseases, Journal of Clinical Periodontology, 18(6), 406-410, July 1991.
 
[2]  Ulvi Kahraman Gursoy, Periodontal Bacteria and Epithelial Cell Interactions: Role of Bacterial Proteins, Eur J Dent. 2, 231-232, October 2008.
 
[3]  Hell K, Characteristics of the ideal antibiotic for prevention of wound sepsis among military forces in the field, Rev Infect Dis. Suppl 2, 164-9, Jan-Feb 1991.
 
[4]  Slots J, Systemic antibiotics in Periodontics, J Periodontol, 75 (11), 1553-65, November 2004.
 
[5]  Jergen Slots, Thomas E., Rams.Antibiotics in periodontal therapy: advantages and disadvantages, Journal of Clinical Periodontology, 17 (1), 479-493, August 1990.
 
[6]  J Berdy, Recent developments of antibiotic research and classification of antibiotics according to chemical structure, Advances in Applied Microbiology, 359-397, 1974.
 
[7]  Walsh, C., Structure and origin of antibiotics, Antibiotics: actions, origins, resistance. 347-359, 2008.
 
[8]  David N Gilbert, MD, Belle L Lee, A randomized comparison of the safety and efficacy of once-daily Gentamicin or thrice-daily Gentamicin in combination with Ticarcillin-Clavulanate, The American Journal of Medicine, 105(3),182-191. September 1998.
 
[9]  B S Speer, N B Shoemaker, Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance, Clin Microbiol Rev. 5(4): 387-399, October 1992.
 
[10]  JA Kelly, O Dideberg, On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target, Science 21, 231(44), 1429-1431, March 1986.
 
[11]  Proctor DB, Baker CG., Treatment of acute necrotizing ulcerative gingivitis with metronidazole, J Can Dent Assoc (Tor), 37(10), 376-80, October 1971.
 
[12]  Robert I Wise, Allan E. Voigt, Origin of Erythromycin-Resistant Strains of Micrococcus Pyogenes in Infections Bacteriophage Types and In Vitro Resistance of Cultures to Antibiotics, AMA Arch Intern Med, 95(3):419-426, 1955.
 
[13]  Rush DE, Abdel-Haq N., Clindamycin versus Unasyn in the treatment of facial cellulitis of odontogenic origin in children, Clin Pediatr., 46(2):154-9, March 2007.
 
[14]  Levine DP. Vancomycin: a history, Clin Infect Dis. 1(42), 5-12, January 2006.
 
[15]  Kelly C. Peach , Walter M. Bray et al, Mechanism of action-based classification of antibiotics using high-content bacterial image analysis, Mol. BioSyst., 9, 1837-1848, 2013.
 
[16]  Kaufman G., Antibiotics: mode of action and mechanisms of resistance, Nursing Standard. 25(42), 49-55, 2011.
 
[17]  Drisko, Nonsurgical periodontal therapy, Periodontology 2000, 25(1), 77-88, February 2001.