Prescription of Prophylactic Antibiotic in Dental Implant among Saudi Population

Sultan Saeed Aldogar Al-Mones^1, , Khalid Alhezaimi² and Sami Shafik²

¹Department of Periodontology, Riyadh Elm University, Riyadh, Saudi Arabia

²Department of Preventive Dental Sciences, Riyadh Elm University, Riyadh, Saudi Arabia

Cite this paper:
Sultan Saeed Aldogar Al-Mones, Khalid Alhezaimi and Sami Shafik. Prescription of Prophylactic Antibiotic in Dental Implant among Saudi Population. International Journal of Dental Sciences and Research. 2020; 8(1):1-6. doi: 10.12691/ijdsr-8-1-1

Abstract

Aim: This study was designed to find out the awareness among the dental practitioners using American Heart Association (AHA) guidelines for dental implants and for prescribing the dosage of Antibiotic Prophylaxis (AP) as per the AHA guidelines. Methodology: A cross-sectional questionnaire projected across the Saudi Arabia among practicing dentists (general and specialists) and dental students (final year undergraduate and postgraduate). The questionnaire was distributed to 1000 dental practitioners, who willingly consented to participate in the study. The questionnaire consists of 11 (either multiple choice or dichotomous) questions regarding the awareness and practice of AHA guidelines for dental implants and prescribing AP pre- or post-dental implants. Statistical analysis was performed using SPSS version 21. A chi-square test was performed with both descriptive and inferential statistics. The level of significance was P ≤0.05. Results: Total responses from 893 (89.3%) participants were received and were considered for statistical analysis. Male and female participants were 485 (54.3%) and 408 (45.7%), respectively. The majority of the participants responded wrongly for prescribing AP for dental implants as a routine practice, immediate implant, and immediate implant with systemic disease. However, the majority of the practitioners responded correctly in prescribing amoxicillin as the first line of AP to be used during implants but with the wrong dosage of the drug. Moreover, more than half of the practitioners answered correctly for prescribing AP to post-operation. The primary factors in prescribing AP for dental implants were selected wrong by a significant number of practitioners. To increase the success of the dental implants, an overwhelming number of the practitioners answered correctly by opting for pre operation use of AP. Conclusion: The present study outlines and indicates the lack of awareness of AHA recommendations and guidelines among dental practitioners in KSA. Besides, it recorded a high number of AP prescriptions during dental implant placement as a routine practice without any supporting evidence.

Keywords:
dental implants antibiotics American heart association antibiotic prophylaxis

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References:

[1]	Ng, P.C.-H., et al., Dental implant practice among Hong Kong general dental practitioners in 2004 and 2008. Implant dentistry, 2011. 20(1): p. 95-105.
[2]	Palma-Carrió, C., et al., Risk factors associated with early failure of dental implants. A literature review. Med Oral Patol Oral Cir Bucal, 2011. 16(4): p. e514-7.
[3]	Peterson, L.J., Antibiotic prophylaxis against wound infections in oral and maxillofacial surgery. Journal of Oral and Maxillofacial Surgery, 1990. 48(6): p. 617-620.
[4]	Esposito, M., M.G. Grusovin, and H.V. Worthington, Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications. Cochrane Database of Systematic Reviews, 2013(7).
[5]	Wilson, W., et al., Prevention of infective endocarditis: guidelines from the American heart association: a guideline from the American heart association rheumatic fever, endocarditis, and Kawasaki disease committee, council on cardiovascular disease in the young, and the council on clinical cardiology, council on cardiovascular surgery and anesthesia, and the quality of care and outcomes research interdisciplinary working group. Circulation, 2007. 116(15): p. 1736-1754.
[6]	Organization, W.H., Antimicrobial resistance: global report on surveillance. 2014: World Health Organization.
[7]	NICE, C.f.C.P.a., Prophylaxis against infective endocarditis: antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional procedures. 2008.
[8]	Daly, C.G., Antibiotic prophylaxis for dental procedures. Australian prescriber, 2017. 40(5): p. 184.
[9]	Murdoch, D.R., et al., Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis–Prospective Cohort Study. Archives of internal medicine, 2009. 169(5): p. 463-473.
[10]	Van der Meer, J., et al., Efficacy of antibiotic prophylaxis for prevention of native-valve endocarditis. The Lancet, 1992. 339(8786): p. 135-139.
[11]	Datta, R., et al., Current trend of antimicrobial prescription for oral implant surgery among dentists in India. Journal of maxillofacial and oral surgery, 2014. 13(4): p. 503-507.
[12]	Khalil, D., et al., Antibiotic prescription patterns among Swedish dentists working with dental implant surgery: adherence to recommendations. Clinical oral implants research, 2015. 26(9): p. 1064-1069.
[13]	AbuKaraky, A.E., et al., Antibiotics prescribing practices in oral implantology among jordanian dentists. A cross sectional, observational study. BMC research notes, 2011. 4(1): p. 266.
[14]	El-Kholey, K.E., et al., Pattern of Antibiotic Prescription for Oral Implant Treatment Among Dentists in Saudi Arabia. Implant dentistry, 2018. 27(3): p. 317-323.
[15]	AboAlSamh, A., et al., Dental Students’ Knowledge and Attitudes towards Antibiotic Prescribing Guidelines in Riyadh, Saudi Arabia. 2018. 6(2): p. 42.
[16]	Al Khuzaei, N.M., et al., Knowledge of antibiotics among dentists in Saudi Arabia. 2017. 9(2): p. 71.
[17]	Al-Qahtani, M.A., et al., Self-medication with antibiotics in a primary care setting in King Khalid University Hospital, Riyadh, Saudi Arabia. Journal of family & community medicine, 2018. 25(2): p. 95.
[18]	Spittle, L.S., et al., Current prescribing Practices for Antibiotic Prophylaxis: A Survey of Dental Practitioners. The journal of contemporary dental practice, 2017. 18(7): p. 559-566.
[19]	Alshaikh, M., A. Mayet, and H. Aljadhey, Medication error reporting in a university teaching hospital in Saudi Arabia. Journal of patient safety, 2013. 9(3): p. 145-149.
[20]	Alnemri, A.R., et al., Misuse of antibiotic: A systemic review of Saudi published studies. Current Pediatric Research, 2016.
[21]	Baadani, A.M., et al., Physicians’ knowledge, perceptions, and attitudes toward antimicrobial prescribing in Riyadh, Saudi Arabia. Saudi medical journal, 2015. 36(5): p. 613.
[22]	Al-Harthi, S.E., et al., Perceptions and knowledge regarding antimicrobial stewardship among clinicians in Jeddah, Saudi Arabia. Saudi medical journal, 2015. 36(7): p. 813.
[23]	Camps-Font, O., et al., Antibiotic prescription for the prevention and treatment of postoperative complications after routine dental implant placement. A cross-sectional study performed in Spain. Journal of clinical and experimental dentistry, 2018. 10(3): p. e264.
[24]	Abdulhak, A.A.B., et al., Non prescribed sale of antibiotics in Riyadh, Saudi Arabia: a cross sectional study. BMC public health, 2011. 11(1): p. 538.
[25]	Lazarou, J., B.H. Pomeranz, and P.N. Corey, Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. Jama, 1998. 279(15): p. 1200-1205.
[26]	Shehab, N., et al., Emergency department visits for antibiotic-associated adverse events. Clinical infectious diseases, 2008. 47(6): p. 735-743.
[27]	Pulcini, C. and I.C. Gyssens, How to educate prescribers in antimicrobial stewardship practices. Virulence, 2013. 4(2): p. 192-202.
[28]	Bax, R., et al., Antibiotic resistance-what can we do? Nature medicine, 1998. 4(5): p. 545-546.
[29]	Memish, Z.A., et al., Streptococcus pneumoniae in Saudi Arabia: antibiotic resistance and serotypes of recent clinical isolates. International journal of antimicrobial agents, 2004. 23(1): p. 32-38.
[30]	Morgan, D.J., et al., Non-prescription antimicrobial use worldwide: a systematic review. The Lancet infectious diseases, 2011. 11(9): p. 692-701.