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International Journal of Clinical and Diagnostic Research
ISSN (Print): 2395-3403 ISSN (Online): 2395-3403 Website: https://www.sciepub.com/journal/ijcdr Editor-in-chief: Apply for this position
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International Journal of Clinical and Diagnostic Research. 2019, 7(6), 124-130
DOI: 10.12691/ijcdr-7-6-1
Open AccessArticle

ROLE OF POLY HEXA METHYLENE BIGUANIDE (PHMB) IN WOUND BED PREPARATION: REPORT OF A SUCCESSFULLY MANAGED CASE

Abhinav Aggarwal1, Ravi Kumar Chittoria1, , Vinayak Chavan2, Chirra Likhitha Reddy3, Saurabh Gupta4, Padmalakshmi Bharathi Mohan5, Imran Pathan6 and Shijina K7

1Department of Plastic Surgery &Telemedicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India- 5006

2Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India-605006.

3Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India-605007.

4Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India-605008.

5Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India-605009.

6Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India-605010.

7Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India-605011.

Pub. Date: December 19, 2019
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Cite this paper:
Abhinav Aggarwal, Ravi Kumar Chittoria, Vinayak Chavan, Chirra Likhitha Reddy, Saurabh Gupta, Padmalakshmi Bharathi Mohan, Imran Pathan and Shijina K. ROLE OF POLY HEXA METHYLENE BIGUANIDE (PHMB) IN WOUND BED PREPARATION: REPORT OF A SUCCESSFULLY MANAGED CASE. International Journal of Clinical and Diagnostic Research. 2019; 7(6):124-130. doi: 10.12691/ijcdr-7-6-1

Abstract

Wound bed preparation is an art. It is a complex process that involves an understanding of the physiology of wound healing, the factors, which disrupt wound healing and methods to overcome them. Necrotizing fasciitis is one of the most challenging wounds to prepare due to rampant infection, debilitated condition of the patient and comorbid conditions. Various modalities have been tried and described for accelerating the wound bed preparation of such chronic wounds. Wound irrigation and dressing is an integral part of wound bed preparation. Poly Hexa Methylene Biguanide (PHMB) and betaine solution is a novel compound that has been introduced for that purpose. PHMB is a heterodisperse mixture of polymers and is a compound belonging to a family of antimicrobial peptides. We tried the solution for a patient with a Fournier’s gangrene (necrotizing fasciitis of the scrotum and groin) and share our experience with the same.

Keywords:
Wound Bed Preparation Poly Hexa Methylene Biguanide (PHMB) Fournier’s gangrene Necrotizing fasciitis

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