A STUDY ON SERUM URIC ACID AND LIVER ENZYMES IN THE GERIATRIC AGE GROUP IN A TERTIARY CARE HOSPITAL

Elteza T J¹, Nirmali M^1, and Tridip K²

¹Department of Biochemistry, Gauhati Medical College & Hospital, Assam.

²Department of Biochemistry, Tezpur Medical College & Hospital, Assam.

Cite this paper:
Elteza T J, Nirmali M and Tridip K. A STUDY ON SERUM URIC ACID AND LIVER ENZYMES IN THE GERIATRIC AGE GROUP IN A TERTIARY CARE HOSPITAL. International Journal of Clinical and Diagnostic Research. 2018; 6(3):76-81. doi: 10.12691/ijcdr-6-3-2

Abstract

Hyperuricemia has long been considered as a cause of gouty arthritis and kidney stones but more recently it has also been implicated in the development of liver dysfunction, hypertension, kidney disease, metabolic syndrome, and cardiovascular disease. It has been suggested that hyperuricaemia can lead to oxidative stress, endothelial dysfunction, insulin resistance and systemic inflammation. This study is done with a view to measure the levels of uric acid and liver enzymes(AST, ALT, GGT) in the geriatric age group and to analyse the results statistically. Case group comprised of 30 person of age>60 years attending geriatric OPD while30 healthy subjects of age<60 years were taken as control. Uric acid, AST, ALT and GGT levels were analysed in both case and control group in Vitros 5600 fully automated analyser. The mean values of uric acid, AST, ALT and GGT were significantly higher in case group as compared with the control.The elevation of serum uric acid levels along with the classical liver enzymes might be a risk factor for incidence of chronic liver disease in the elderly.

Keywords:
Uric acid Aspartate transaminase Alanine transaminase Gamma glutamyl transpeptidase

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