HYPOGONADOTROPHIC HYPOGONADISM WITH SYNKINESIA AND DERANGED PITUITARY PROFILE: AN ENIGMA OF FINDINGS AND DILEMMA IN DIAGNOSIS

Satyam Chakraborty¹, Ashish Kumar Basu², Animesh Maiti³, Anirban Sinha⁴, Lakshmi Dey⁵, Praveen Devarbhavi⁶, Soumita Mondal⁷ and Subir Swar⁸

¹Department of Endocrinology and Metabolism, Medical College and Hospital, 88, College Street; Kolkata-700073.

²Department of Endocrinology and Metabolism, Medical College and Hospital, 88, College Street; Kolkata-700074.

³Department of Endocrinology and Metabolism, Medical College and Hospital, 88, College Street; Kolkata-700075.

⁴Department of Endocrinology and Metabolism, Medical College and Hospital, 88, College Street; Kolkata-700076.

⁵Department of Endocrinology and Metabolism, Medical College and Hospital, 88, College Street; Kolkata-700077.

⁶Department of Endocrinology and Metabolism, Medical College and Hospital, 88, College Street; Kolkata-700078.

⁷Department of Endocrinology and Metabolism, Medical College and Hospital, 88, College Street; Kolkata-700079.

⁸Department of Endocrinology and Metabolism, Medical College and Hospital, 88, College Street; Kolkata-700080.

Cite this paper:
Satyam Chakraborty, Ashish Kumar Basu, Animesh Maiti, Anirban Sinha, Lakshmi Dey, Praveen Devarbhavi, Soumita Mondal and Subir Swar. HYPOGONADOTROPHIC HYPOGONADISM WITH SYNKINESIA AND DERANGED PITUITARY PROFILE: AN ENIGMA OF FINDINGS AND DILEMMA IN DIAGNOSIS. International Journal of Clinical and Diagnostic Research. 2016; 4(6):130-134. doi: 10.12691/ijcdr-4-6-3

Abstract

A 14-year-old Indian male presented with complaints of growth failure which parents noticed for the last four years & no development of secondary sexual characteristics causing significant parental anxiety. Neurological examination was normal except the child exhibited mirror movements in the upper extremities. MRI (magnetic resonance imaging) of the pituitary & the hypothalamus showed “a pituitary macro-adenoma with supra-sellar extension with chiasmal compression without cavernous sinus involvement”. Our presentation is probably the first case which revealed synkinetic movements in a case of pituitary macroadenoma. At the same time our case calls for a study of the inhibitory association tracts which physiologicallyprevents mirror movements.

Keywords:
Hypogonadotrophic hypogonadism Synkinesia Pituitary macroadenoma

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