International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: https://www.sciepub.com/journal/ijcd Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2017, 5(2), 62-68
DOI: 10.12691/ijcd-5-2-5
Open AccessArticle

Celiac Disease and Gluten-free Diet in Portuguese Children – An Anthropometric Marker Contribution Assessment

Patrícia Soares1, Piedade Sande Lemos2, Ana Maria Pires1, 3 and Ana Cláudia Cavaco de Sousa1,

1Universidade Atlântica – Centro de Estudos, Sociedade, Organizações e Bem-Estar (CESOB)

2Nova Medical School, Hospital Amadora-Sintra, Hospital CUF-Cascais

3Faculdade de Ciências da Universidade de Lisboa – Centre for Ecology, Evolution and Environmental Changes (cE3c)

Pub. Date: June 02, 2017

Cite this paper:
Patrícia Soares, Piedade Sande Lemos, Ana Maria Pires and Ana Cláudia Cavaco de Sousa. Celiac Disease and Gluten-free Diet in Portuguese Children – An Anthropometric Marker Contribution Assessment. International Journal of Celiac Disease. 2017; 5(2):62-68. doi: 10.12691/ijcd-5-2-5

Abstract

Celiac disease is an autoimmune disease that is expressed by chronic food sensitivity to gluten, having as typical symptoms diarrhea and weight loss. The present study has evaluated anthropometric marker progressions in 61 Portuguese children with celiac disease, at diagnosis time and at the study time, comparing these variations with the intake of gluten free products. Data from 61 children (59.0 % girls) with celiac disease were evaluated, following a gluten free diet for 5.0 ± 4.6 years. Statistical t-test analysis of pBMI at diagnosis and at study time, revealed a positive increase with statistical significance for both girls and boys (p = 0.008). The differences between ingested and recommended values were quantified and confirming the increase in total energy consumption and carbohydrates. Following a gluten free diet allows the recovery of the nutritional status in most children; however, nutritional counseling seems mandatory to avoid nutrient imbalances and further health issues.

Keywords:
celiac disease gluten free diet children natural gluten free products processed gluten free products

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Bai JC, Fried M, Corazza GR, Schuppan D, Farthing M, Catassi C, Greco L, Cohen H, Ciacci C, Eliakim R, Fasano A, González A, Krabshuis JH, LeMair A. World Gastroenterology Organisation global guidelines on celiac disease. Journal of Clinical Gastroenterology. 2013; 47(2): 121-6.
 
[2]  Lerner A, Jeremias P, Matthias T. The World Incidence and Prevalence of Autoimmune Diseases is Increasing. International Journal of Celiac Disease. 2015; 3(4): 151-155.
 
[3]  Lerner A, Jeremias P, Matthias T. The World Incidence of Celiac Disease in Increasing: a Review. International Journal of Recent Scientific Research. 2015; 7 (7): 5491-5496.
 
[4]  Hoffenberg EJ, MacKenzie T, Barriga KJ, Eisenbarth GS, Bao F, Haas JE, Erlich H, Bugawan TI, Sokol RJ, Taki I, Norris JM, Rewars M. A prospective study of the incidence og childhood celiac disease. Journal Pediatrics. 2003; 143: 308-314.
 
[5]  Tack GJ, Verbeek WHM, Schreurs MWJ, Mulder CJJ. The spectrum of celiac disease: epidemiology, clinical aspects and treatment. Nature Reviews Gastroenterology and Hepatology. 2010; 7: 204-213.
 
[6]  Catassi C, Gatti S, Fasano A. The new epidemiology of celiac disease. Journal of Pediatric Gastroenterology and Nutrition. 2014; 59(Suppl 1): S7-9.
 
[7]  Myléus A, Ivarsson A, Webb C, Danielsson L, Hernell O, Högberg L, Karlsson E, Lagerqvist C, Norström F, Rosén A, Sandström O, Stenhammar J, Stenlund H, Wall S, Carlsson A. Celiac disease revealed in 3% of Swedish 12-years-orld born during an epidemic. Journal of Pediatrics Gastroenterology Nutrition. 2009; 49: 170-176.
 
[8]  Antunes H. First study on the prevalence of celiac disease in a Portuguese population. Journal Pediatrics of Gastroenterology Nutrition. 2002; 34: 240.
 
[9]  Antunes H, Abreu I, Nogueiras A, Sá C, Gonçalves C, Cleto P, Garcia F, Alves Adelaide, Lemos D. Primeira Determinação de Prevalência de Doença Celíaca numa População Portuguesa [First Prevalence of Celiac Disease in a Portuguese Population]. Acta Médica Portuguesa. 2006; 19: 115-20.
 
[10]  Oliveira JRH, Cabral AJ, Ferreira E, Capelinha F, Spínola H, Gonçalves R. Celiac disease in children from Madeira Island and its prevalence in first degree relatives. Arquives of Gastroenterology. 2014; 51(2): 151-154.
 
[11]  Valletta E, Fornaro M, Cipolli M, Conte S, Bissolo F, Danchielli C. Celiac disease and obesity: need for nutritional follow-up after diagnosis. European Journal of Clinical Nutrition. 2010; 64(11): 1371-1372.
 
[12]  Livshits OE, Shaoul R, Reifen R, Matthias T, Lerner A. Can Celiac Disease Present Along With Childhood Obesity? International Journal of Celiac Disease. 2017; 5(1): 19-23.
 
[13]  Telega G, Bennet TR, Werlin S. Emerging new clinical patterns in the presentation of celiac disease. Archives of Pediatrics & Adolescent Medicine. 2008; 162(2): 164-168.
 
[14]  Aurangzeb B, Leach ST, Lemberg DA, Day AS. Nutritional status of children with coeliac disease. Acta Pediatrica: 2010; 99: 1020-25.
 
[15]  Hernandez L, Green PH. Extraintestinal manifestations of celiac disease. Current Gastroenterology Reports. 2006; 8(5): 383-9.
 
[16]  Balamtekin N, Uslu N, Baysoy G, Usta Y, Demir H, Saltik-Temizel IN, Ozen H, Gürakan F, Yüce A. The presentation of celiac disease in 220 Turkish children. The Turkish Journal of Pediatrics. 2010; 52(3): 239-44.
 
[17]  Lerner A, Matthias T. Extra Intestinal Manifestations of CD: Common Pathways in the Gut-remote Organs’ Axes. International Journal of Celiac Disease. 2017; 5(1): 1-5.
 
[18]  Castillo NE, Theethira TG, Leffler DA. The present and the future in the diagnosis and management of celiac disease. Gastroenterology Report. 2015; 3(1): 3-11.
 
[19]  Bascuñán, KA, Vespa MC, Araya M. Celiac disease: understanding the gluten-free diet. European Journal of Nutrition: 2016: 1-11.
 
[20]  Vici G, Belli L, Biondi M, Polzonetti V. Gluten free diet and nutrient deficiencies: A review. Clinical Nutrition. 2016; 35 (6): 1236-1241.
 
[21]  Rashid M, Cranney A, Zarkadas M, Graham ID, Switzer C, Case S, Molloy M, Warren RE, Burrows V, Butzner JD. Celiac disease: evaluation of the diagnosis and dietary compliance in Canadian children. Pediatrics. 2005; 116(6):754-759.
 
[22]  Errichiello S, Esposito O, Di Mase R, Camarca ME, Natale C, Limongelli MG, Marano C, Coruzzo A, Lombardo M, Strisciuglio P, Greco L. Celiac disease: predictors of compliance with a gluten-free diet in adolescents and young adults. Journal of Pediatric Gastroenterology and Nutrition. 2010; 50(1): 54-60.
 
[23]  Roma E, Roubani A, Kolia E, Panayiotou J, Zellos A, Syriopoulou VP. Dietary compliance and life style of children with coeliac disease. Journal of Human Nutrition and Dietetics . 2010; 23(2): 176-82.
 
[24]  Kurppa K, Lauronen O, Collin P, Ukkola A, Laurila K, Huhtala H, Mäki M, Kaukinen K. Factors associated with dietary adherence in celiac disease: a nationwide study. Digestion. 2012; 86(4): 309-14.
 
[25]  Zarkadas M, Dubois S, MacIsaac K, Cantin I, Rashid M, Roberts KC, La Vieille S, Godefroy S, Pulido, OM. Living with coeliac disease and a gluten-free diet: a Canadian perspective. Journal of Human Nutrition and Dietetics. 2013; 26(1): 10-23.
 
[26]  Samasca G, Sur G, Lupan I, Deleanu D. Gluten-free diet and quality of life in celiac disease. Gastroenterology and Hepatology from Bed to Bench. 2014; 7(3): 139-43.
 
[27]  Samasca G, Lerner A, Sur G, Lupan L, Makovichy P, Matthias T, Freeman HJ. Challenging in Glute-free diet in celiac disease: Prague consensus. European Journal of Clinical Investigation. 2017.
 
[28]  Real A, Comino I, Lorenzo L, Merchán F, Gil-Humanes J, Giménez AJ, López-Casado MA, Torres MI, Cebolla Á, Sousa C, Barro F, Pistón F. Molecular and Immunological Characyerization of Gluten Proteins Isolated from Oat Cultivars That Differ in Toxicity for Celiac Disease. PLoS ONE. 2012; 7(12): e48365.
 
[29]  Comino I, Moreno ML, Real A, Rodríguez-Herrera A, Barro F, Sousa C. The Gluten-Free Diet: Testing Alternative Cereals Tolerated by Celiac Patients. Nutrients. 2013; 5: 4250-4268.
 
[30]  Lerner A, Matthias. Changes in intestinal tight junction permeability associated with industrial food additives explain the riseng incidence of autoimmune disease. Autoimmunity Reviews. 2015; 14: 479-489.
 
[31]  Hopman EGD, le Cessie S, von Blomberg BME, Mearin ML. Nutritional management of the gluten-free diet in young people with celiac disease in The Netherlands. Journal of Pediatric Gastroenterology and Nutrition. 2006; 43(1): 102-8.
 
[32]  Zuccotti G, Fabiano V, Dilillo D, Picca M, Cravidi C, Brambilla P. Intakes of nutrients in Italian children with celiac disease and the role of commercially available gluten-free products. Journal of Human Nutrition and Dietetics. 2013; 26(5): 436-444.
 
[33]  Brambilla P, Picca M, Dilillo D, Meneghin F, Cravidi C, Tischer MC, Vivaldo T, Bedogni G, Zuccotti GV. Changes of body mass index in celiac children on a gluten-free diet. Nutrition, Metabolism, and Cardiovascular Diseases. 2013; 23(3): 177-82.
 
[34]  Barton SH, Kelly DG, Murray JA. Nutritional Deficiencies in Celiac Disease. Gastroenterology Clinics of North America. 2007; 36: 93-108.
 
[35]  Venkatasubramani N, Telega G, Werlin SL. Obesity in pediatric celiac disease. Journal of Pediatric Gastroenterology Nutrition. 2010; 51: 295-297.
 
[36]  Diamanti A, Capriati T, Basso MS, Panetta F, Laurora VMC, Bellucci F, Cristofori F, Francavilla R. Celiac Disease and Overweight in Children: An Update. Nutrients. 2014; 6: 207-220.
 
[37]  Andrews D, Nonnecke B, Preece J. Electronic survey methodology: A case study in reaching hard to involve Internet Users. International Journal of Human-Computer Interaction. 2003; 16:185-210.
 
[38]  Wright KB. Researching Internet-Based Populations: Advantages and Disadvantages of Online Survey Research, Online Questionnaire Authoring Software Packages and Web Survey Services. Journal of Computer-Mediated Communication. 2005; 10: 00-00.
 
[39]  Nulty DD. The adequacy of response rates to online and paper surveys: what can be done?. Assessment & Evaluation in Higher Education. 2008; 33: 301-314.
 
[40]  Direção Geral de Saúde (DGS). Actualização das curvas de crescimento. 2006. Available: http://www.dgs.pt.
 
[41]  Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA). Tabela da Composição de Alimentos. 2010.
 
[42]  Direção Geral de Saúde (DGS). Plataforma nacional contra a obesidade: Obesidade Infantil. 2015. Available: http://www.plataformacontraaobesidade.dgs.pt.
 
[43]  World Health Organization (WHO) Human energy requirements. 2004.
 
[44]  World Health Organization (WHO). European Guideline for children and young people (7-18 years). 2006.
 
[45]  Whitley E Ball J. Statistics review 6: Nonparametric methods. BioMed Central Ltd. 2002. Online at http://ccforum.com/content/6/6/509.
 
[46]  Husby S, Koletzko S, Korponay-Szabó IR, Mearin ML, Phillips A, Shamir R, Troncone R, Giersiepen K, Branski D., Catassi C, Lelgeman M., Mäki, Ribes-Koninckx C, Ventura A, Zimmer KP. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease. Journal of Pediatric Gastroenterology & Nutrition. 2012; 54 (1): 136-160.
 
[47]  Ivarsson A, Persson LÅ, Nyström L, Hernell O. The Swedish coeliac disease epidemic with a prevailing twofold higher risk in girls to boys may reflect gender specific risk factors. European Journal of Epidemiology: 2003; 18: 677-84.
 
[48]  Öhlund K, Olsson C, Hernell O, Öhlund I. Dietary shortcomings in children on a gluten-free diet. Journal of Human Nutrition and Dietetics. The Official Journal of the British Dietetic Association. 2010; 23(3): 294-300.
 
[49]  Barera G, Mora S, Brambilla P, Ricotti A, Menni L, Beccio S, Bianchi C. Body composition in children with celiac disease and the effects of a gluten-free diet: a prospective case-control study. The American Journal of Clinical Nutrition. 2000; 72(1): 71-5.
 
[50]  Niewinski M. Advances in Celiac Disease and Gluten-Free Diet. Journal of the American Dietetic Association. 2008: 661-672.
 
[51]  Penagini F, Dilillo D, Meneghin F, Mameli C, Fabiano V, Zuccotti GV. Gluten-Free Diet in Children: Ana Approach to a Nutritionally Adequate and Balanced Diet. Nutrients, 2013; 5: 4553-4565.
 
[52]  Reilly NR, Aguilar K, Hassid BG, Cheng J, Defelice, AR, Kazlow P, Bhagat G, Green PH. Celiac disease in normal-weight and overweight children: clinical features and growth outcomes following a gluten-free diet. Journal of Pediatric Gastroenterology and Nutrition. 2011; 53(5): 528-31.
 
[53]  Dickey W, Kearney N. Overweight in celiac disease: Prevalence, clinical characteristics, and effect of a gluten-free diet. American Journal of Gastroenterology. 2006; 101: 2356-2359.
 
[54]  Ferrara P, Cicala M, Tiberi E, Spadaccio C, Marcella L, Gatto A, Calzolari P, Castellucci G. High fat consumption in children with celiac disease. Acta GastroEnterologica Belgium. 2009; 72(3): 296-300.
 
[55]  Martin J, Geisel T, Maresch C, Krieger K, Stein J. Inadequate nutrient intake in patients with celiac disease: results from a german dietary survey. Digestion. 2013; 87: 240-246.
 
[56]  Jasthi B, Stevenson J, Harnack L. Comparation of nutrient composition of gluten-containing and gluten-free sliced breads and sparghetti noodles. 38th National nutrient databanck conference, Portland (USA). 2014.
 
[57]  Lee AR, Ng DL, Dave E, Ciaccio EL, Green PHR. The effect of substituting alternative grains in the diet on the nutritional profile of the gluten-free diet. Journal of Human Nutrition and Dietetics. 2009; 22: 359-363.
 
[58]  Wild D, Robins GG, Burley VJ, Howdle PD. Evidence of high sugar intake, and low fibre and mineral intake, in the gluten-free diet. Alimentary Pharmacology and Therapeutics. 2010; 32: 573-581.
 
[59]  Shepherd SJ, Gibson PR. Nutritional inadequacies of the gluten-free diet in both recently-diagnosed and long-term patients with coeliac disease. Journal of Human Nutrition and Dietetics. 2013; 26(4): 349-358.
 
[60]  Castillo-Duran C, Pacheco-Acosta J. New Insights into Celiac Disease and Micronutrient Deficiencies in Pediatrics. International Journal of Celiac Disease. 2014; 2 (4): 119-20.
 
[61]  Miranda J, Lasa A, Bustamante MA, Churruca I, Simon E. Nutritional Differences Between a Gluten-free Diet and a Diet Containing Equivalent Products with Gluten. Plant Foods Human Nutrition. 2014; 69: 182-187.
 
[62]  Afonso D, Jorge R, Moreira AC. Alimentos Com e Sem Glúten – Análise Comparativa de Preços de Mercado. [Gluten and Gluten-Free Products – Price Difference]. Acta Portuguesa de Nutrição. 2016: 10-16.